Accéder au contenu
Merck
Toutes les photos(1)

Documents

1.01728

Sigma-Aldrich

OSTEOSOFT®

mild decalcifier-solution for histology

Se connecterpour consulter vos tarifs contractuels et ceux de votre entreprise/organisme


About This Item

Code UNSPSC :
12352401
Nomenclature NACRES :
NA.21

Niveau de qualité

Forme

liquid

IVD

for in vitro diagnostic use

Couleur

dark red

pH

7.0-7.3 (20 °C in H2O)

Densité

1.10 g/mL at 20 °C

Application(s)

diagnostic assay manufacturing
hematology
histology

Température de stockage

15-25°C

Description générale

This ready-to-use product, OSTEOSOFT® - mild decalcifier-solution for histology, has been specifically developed for human cell diagnostics in humans and is used for the demineralization and decalcification of bones, punched bone-marrow specimens, and other hard tissue of human origin.
Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®(Product number 1.01736), can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and acetic acid. The amount of OSTEOSOFT®needed is dependent upon on the size, type and thickness of the material. Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. OSTEOSOFT® is used only once and fresh solution must be used for each tissue. The quantity of OSTEOSOFT® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

Informations légales

OSTEOMOLL is a registered trademark of Merck KGaA, Darmstadt, Germany
OSTEOSOFT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogrammes

Health hazardCorrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Eye Dam. 1 - STOT RE 2 Inhalation

Organes cibles

Respiratory Tract

Code de la classe de stockage

12 - Non Combustible Liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

Déjà en possession de ce produit ?

Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Ivana Kurelac et al.
Journal of clinical medicine, 8(12) (2019-12-15)
A cogent issue in cancer research is how to account for the effects of tumor microenvironment (TME) on the response to therapy, warranting the need to adopt adequate in vitro and in vivo models. This is particularly relevant in the

Contenu apparenté

Learn about the criticality of biological tissue staining for research and clinical pathology using standard and special stains and dyes.

Apprenez-en davantage sur le caractère critique de la coloration de tissus biologiques pour la recherche et la biologie médicale en utilisant des colorants standards et spéciaux.

Notre équipe de scientifiques dispose d'une expérience dans tous les secteurs de la recherche, notamment en sciences de la vie, science des matériaux, synthèse chimique, chromatographie, analyse et dans de nombreux autres domaines..

Contacter notre Service technique