1643306

Tamoxifen citrate

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Tamoxifen citrate salt, (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
• Fórmula empírica (notación de Hill): C₂₆H₂₉NO · C₆H₈O₇
• Número de CAS: 54965-24-1
• Peso molecular: 563.64
• Número MDL: MFCD00058321
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329751221
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: tamoxifen
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: OC(=O)CC(O)(CC(O)=O)C(O)=O.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCN(C)C)cc3
• InChI: 1S/C26H29NO.C6H8O7/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10/h5-18H,4,19-20H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)/b26-25-;
• Clave InChI: FQZYTYWMLGAPFJ-OQKDUQJOSA-N
• Información sobre el gen: human ... ESR1(2099)

Descripción

Descripción general

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Tamoxifen citrate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Tamoxifen Citrate Tablets

Acciones bioquímicas o fisiológicas

Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response modifiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08,GHS07,GHS09
• Palabra de señalización: Danger
• Frases de peligro: H302,H350,H360D,H410
• Consejos de prudencia: P201 - P273 - P301 + P312 + P330 - P308 + P313
• Clasificaciones de peligro: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable