1176506

Dexamethasone 21-acetate

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Fórmula empírica (notación de Hill): C₂₄H₃₁FO₆
• Número de CAS: 1177-87-3
• Peso molecular: 434.50
• Beilstein: 2342608
• Número MDL: MFCD00027407
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329749549
• NACRES: NA.24

Propiedades

• origen biológico: synthetic
• grado: pharmaceutical primary standard
• Agency: USP
• presión de vapor: <0.0000001 kPa ( 25 °C)
• familia API: dexamethasone
• Formulario: powder
• envase: pkg of 200 mg
• fabricante / nombre comercial: USP
• color: white
• mp: 460.4-464 °F (238—240°C)
• solubilidad: acetone: freely soluble; dichloromethane: slightly soluble; methanol: freely soluble; water: practically insoluble
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• temp. de almacenamiento: 2-8°C
• cadena SMILES: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• Clave InChI: AKUJBENLRBOFTD-RPRRAYFGSA-N
• Información sobre el gen: human ... NR3C1(2908)

Descripción

Descripción general

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids,[1] commonly used as a pharmaceutical ingredient in creams,[2] ointments,[3] microemulsions, lotions, aerosols, etc.[4]
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicación

Dexamethasone acetate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Betamethasone Acetate
• Ciprofloxacin and Dexamethasone Otic Suspension
• Dexamethasone
• Dexamethasone Acetate
• Dexamethasone Acetate Injectable Suspension

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Pictogramas: GHS08
• Palabra de señalización: Danger
• Frases de peligro: H360FD
• Consejos de prudencia: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Clasificaciones de peligro: Repr. 1B
• Código de clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable