V4890

Vindesine sulfate salt hydrate

≥95% (HPLC)

• Sinónimos: 3-(Aminocarbonyl)-O4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine sulfate salt hydrate, Desacetylvinblastine amide sulfate salt hydrate
• Fórmula empírica (notación de Hill): C₄₃H₅₅N₅O₇ · H₂SO₄ · xH₂O
• Número CAS: 59917-39-4
• Peso molecular: 852.00 (anhydrous basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329829055
• NACRES: NA.77
• Assay: ≥95% (HPLC)
• Form: powder

Propiedades

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: off-white to light yellow
• solubility: deionized water: ≥50 mg/mL
• originator: Eli Lilly
• storage temp.: −20°C
• SMILES string: O.OS(O)(=O)=O.CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@H]7[C@](O)([C@H](O)[C@]8(CC)C=CC[N@H]9CC[C@]67[C@H]89)C(N)=O)C1
• InChI: 1S/C43H55N5O7.H2O4S.H2O/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-47(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)54-4)46(3)35-41(28)15-18-48-16-10-14-40(7-2,34(41)48)36(49)43(35,53)37(44)50;1-5(2,3)4;/h8-12,14,19-20,25,34-36,45,49,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H2,44,50);(H2,1,2,3,4);1H2/t25-,34+,35-,36-,39+,40-,41-,42+,43+;;/m1../s1
• InChI key: TUDLKTILIBRXNU-RIHOAIHNSA-N

Descripción

Biochem/physiol Actions

Microtubule inhibitor

Microtubule inhibitor. Vindesine binds to and stabilizes tubulin, thereby preventing tubulin polymerization, preventing mitosis, and arresting cells in metaphase.

Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable