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S6948

SGK2, active, GST tagged human

PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution

Sinónimos:

H-SGK2, dJ138B7.2

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Tamaño de envaseSKUDisponibilidadPrecio
10 μg
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385,00 €

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NACRES:
NA.32
UNSPSC Code:
12352200
Specific activity:
70-94 nmol/min·mg
Assay:
≥70% (SDS-PAGE)
Recombinant:
expressed in baculovirus infected Sf9 cells

385,00 €


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recombinant

expressed in baculovirus infected Sf9 cells

Quality Level

product line

PRECISIO® Kinase

assay

≥70% (SDS-PAGE)

form

buffered aqueous glycerol solution

specific activity

70-94 nmol/min·mg

mol wt

~71 kDa

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... SGK2(10110)

Biochem/physiol Actions

SGK2 is a member of the serum- and glucocorticoid-induced kinases (SGK) which are serine-threonine kinases and belong to the "AGC" kinase subfamily, which includes protein kinases A, G, and C, and its catalytic domain is most similar to protein kinase B (PKB).SGK2, like the other two isoforms SGK1 and SGK3, is stimulated by insulin and insulin-like growth factor-1 (IGF-1), and has been shown to enhance Na(+)/K(+)-ATPase activity in a variety of cells.

Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.

Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo
S7570SAB1406925SAB1410063
assay

≥70% (SDS-PAGE)

assay

≥75% (SDS-PAGE)

assay

-

assay

-

specific activity

70-94 nmol/min·mg

specific activity

100 units/mg protein (Bradford)

specific activity

-

specific activity

-

Gene Information

human ... SGK2(10110)

Gene Information

human ... SGK2(10110)

Gene Information

human ... SGK2(10110)

Gene Information

human ... SGK2(10110)

form

buffered aqueous glycerol solution

form

aqueous glycerol solution

form

buffered aqueous solution

form

buffered aqueous solution

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in E. coli

recombinant

-

recombinant

-

UniProt accession no.

Q9HBY8

UniProt accession no.

Q9HBY8

UniProt accession no.

Q9HBY8

UniProt accession no.

Q9HBY8


Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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Contenido relacionado

Instructions


Christoph Boehmer et al.
Biochemical and biophysical research communications, 313(4), 998-1003 (2004-01-07)
Renal tubular citrate transport is accomplished by electrogenic Na(+) coupled dicarboxylate transporter NaDC-1, a carrier subjected to regulation by acidosis. Trafficking of the Na(+)/H(+) exchanger NHE3 is controlled by NHE regulating factors NHERF-1 and NHERF-2 and the serum and glucocorticoid
T Kobayashi et al.
The Biochemical journal, 344 Pt 1, 189-197 (1999-11-05)
The catalytic domain of serum- and glucocorticoid-induced protein kinase (SGK) is 54% identical with protein kinase B (PKB) and, like PKB, is activated in vitro by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and in vivo in response to signals that activate phosphatidylinositol



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SKUGTIN
S6948-10UG04061837756542

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