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S3884

Sauvagine

≥97% (HPLC)

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Fórmula empírica (notación de Hill):
C202H346N56O63S
Número CAS:
Peso molecular:
4599.31
UNSPSC Code:
12352200
NACRES:
NA.32
MDL number:


assay

≥97% (HPLC)

storage temp.

−20°C

InChI key

ILCVKEBXPLEGOY-ZLFMSJRASA-N

General description

Sauvagine is a polypeptide derived from the frog skin. It belongs to the CRH (corticotropin releasing factor) family. Sauvagine is made of 40 amino acids. It may also be found in the brain of mammals.

Biochem/physiol Actions

A peptide related to CRF and urotensin 1 that was first isolated from the skin of the frog Phyllomedusa sauvagei. Potent releaser of ACTH and β-endorphin from the anterior pituitary.
Sauvagine helps to liberate ACTH (adrenocorticotropic hormone) from the pituitary cells of rat. It has several important functions in the cardiovascular, endocrine and renal systems.

Other Notes

Lyophilized from 0.1% TFA in H2O


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Hormones and behavior, 50(2), 223-236 (2006-04-29)
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David A Lovejoy et al.
General and comparative endocrinology, 146(1), 1-8 (2006-02-14)
The corticotropin-releasing factor (CRF) family of peptides consists of four distinct paralogs found on separate chromosomes in vertebrates. Among invertebrates, the family has been relatively well characterized in the insects where at least 2 or 3 paralogs, a CRF-binding protein
Satoko Ise et al.
Brain research, 1234, 59-65 (2008-08-16)
An infant animal isolated from its mother emits vocalizations spanning from the audible to the ultrasonic. These vocalizations are believed to represent distress signals from the pup. However, the neurobiological basis for vocalizations elicited by isolation has not been well



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SKUGTIN
S3884-250UG04061832677774
S3884-.5MG04061832677750

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