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RAB0707

Human LDLR / Low-density Lipoprotein Receptor ELISA Kit

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NACRES:
NA.32
UNSPSC Code:
41116158
Gene information:
human ... LDLR(3949)
Input:
sample type cell culture supernatant(s)
sample type plasma
sample type serum
Species reactivity:
human
Storage temp.:
−20°C
Shipped in:
wet ice
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species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 8.19-2000 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... LDLR(3949)

General description

The antibody pair provided in this kit recognizes human Low-density Lipoprotein Receptor.
LDLR (low density lipoprotein receptor) codes for a transmembrane receptor glycoprotein, containing 860 amino acids and is mapped to human chromosome 19p13.2.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

LDLR′s (low density lipoprotein receptor) major function is to regulate the level of lipoprotein particles by mediating the clearance of LDL-cholesterol and triglyceride through receptor mediated endocytosis. LDLR is involved in proliferation by providing cholesterol for membrane synthesis.[1] The LDLR gene is a target for treating cardiovascular diseases. Mutation in the gene causes familial hypercholesterolemia.

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

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Este artículo
RAB0680RAB0652RAB0692
species reactivity

human

species reactivity

human

species reactivity

human

species reactivity

human

Gene Information

human ... LDLR(3949)

Gene Information

human ... IGF2R(3482)

Gene Information

human ... EDA2R(60401)

Gene Information

human ... IL1RL2(8808)

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

input

sample type cell culture supernatant(s)
sample type plasma
sample type serum

input

sample type plasma
sample type cell culture supernatant(s)
sample type serum

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 8 pg/mL
standard curve range: 8.19-2000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.27 ng/mL
standard curve range: 0.274-200 ng/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 10 pg/mL
standard curve range: 10.24-2500 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 24 pg/mL
standard curve range: 24.58-6000 pg/mL

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric


Los componentes del kit también están disponibles por separado

Referencia del producto
Descripción
SDS & Precios

  • ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)
    SDS

  • ELISA Stop Solution (Item I)
    SDS

  • 20X Wash Buffer (Item B)
    SDS

pictograms

Corrosion

signalword

Warning

hcodes

Hazard Classifications

Met. Corr. 1

Clase de almacenamiento

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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Contenido relacionado


Daniel S Hsia et al.
The British journal of nutrition, 124(6), 577-585 (2020-04-18)
Cranberries are high in polyphenols, and epidemiological studies have shown that a high-polyphenol diet may reduce risk factors for diabetes and CVD. The present study aimed to determine if short-term cranberry beverage consumption would improve insulin sensitivity and other cardiovascular
Mutational screening in the LDLR gene among patients presenting familial hypercholesterolemia in the Southeast of Brazil.
Molfetta G A, et al.
Genetics and molecular research : GMR, 16(3) (2017)
5-Azacytidine engages an IRE1?-EGFR-ERK1/2 signaling pathway that stabilizes the LDL receptor mRNA.
Mnasri N, et al.
Biochimica et Biophysica Acta - Gene Regulatory Mechanisms, 1861(1), 29-40 (2018)



Número de artículo de comercio global

SKUGTIN
RAB0707-1KT04061835164929

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