Saltar al contenido
Merck

Saltar a

M3074

MMPIP

≥98% (HPLC)

Sinónimos:

6-(4-Methoxyphenyl)-5-methyl-3-(4-pyridinyl)-isoxazolo[ 4,5-c]pyridin-4(5H)-one

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas
Tamaño de envaseSKUDisponibilidadPrecio
5 mg
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
119,00 €
25 mg
Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad
472,00 €

Acerca de este artículo

Fórmula empírica (notación de Hill):
C19H15N3O3
Número CAS:
Peso molecular:
333.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
Storage condition:
desiccated

119,00 €


Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad

Solicite una orden a granel
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle


Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: ≥10 mg/mL

originator

Merck & Co., Inc., Kenilworth, NJ, U.S.

storage temp.

room temp

SMILES string

COc1ccc(cc1)C2=Cc3onc(-c4ccncc4)c3C(=O)N2C

InChI

1S/C19H15N3O3/c1-22-15(12-3-5-14(24-2)6-4-12)11-16-17(19(22)23)18(21-25-16)13-7-9-20-10-8-13/h3-11H,1-2H3

InChI key

PDWYBOZNEVALOV-UHFFFAOYSA-N

Biochem/physiol Actions

MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7).
MMPIP is a potent, selective, allosteric antagonist of metabotropic glutamate receptor 7 (mGluR7). It also displays intrinsic activity and acts as an inverse agonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 1

Este artículo
PZ0357SML0334I7160
assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

≥98% (HPLC)

form

powder

form

powder

form

powder

form

solid

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage temp.

room temp

storage condition

desiccated

storage condition

-

storage condition

desiccated

storage condition

desiccated

solubility

DMSO: ≥10 mg/mL

solubility

DMSO: 30 mg/mL, clear

solubility

H2O: >10 mg/mL

solubility

DMSO: >20 mg/mL


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos


Artículos

DISCOVER Bioactive Small Molecules for Neuroscience

Sigma-Aldrich offers many products related to G-protein family glutamate receptors for your research needs.


Juan Du et al.
Nature, 594(7864), 589-593 (2021-06-18)
The metabotropic glutamate receptors (mGlus) are involved in the modulation of synaptic transmission and neuronal excitability in the central nervous system1. These receptors probably exist as both homo- and heterodimers that have unique pharmacological and functional properties2-4. Here we report
Paulina Cieślik et al.
Frontiers in molecular neuroscience, 11, 316-316 (2018-10-09)
The data concerning antipsychotic-like activity of negative allosteric modulators (NAMs)/antagonists of mGlu7 receptors are limited. The only available ligands for this receptor are MMPIP and ADX71743. In the present studies, we used stable cell line expressing mGlu7 receptor and it
Sinead E Shortall et al.
Molecular neurobiology, 57(8), 3439-3457 (2020-06-14)
Despite several compounds entering clinical trials for the negative and cognitive symptoms of schizophrenia, few have progressed beyond phase III. This is partly attributed to a need for improved preclinical models, to understand disease and enable predictive evaluation of novel



Número de artículo de comercio global

SKUGTIN
M3074-5MG04061832072180
M3074-25MG04061832072173

Preguntas

Revisiones

Sin puntuación

Filtros activos