F7807
Prostaglandin F Synthase human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Sinónimos:
17-beta-hydroxysteroid dehydrogenase type 5, AKR1C3, aldo-keto reductase family 1 member C3, indanol dehydrogenase
Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Cambiar Vistas
| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|
Acerca de este artículo
Número CAS:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Specific activity:
≥0.4 μmol/mg protein
Assay:
≥90% (SDS-PAGE)
Recombinant:
expressed in E. coli
En este momento no podemos mostrarle ni los precios ni la disponibilidad
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle1 of 1
Este artículo | |
|---|---|
| specific activity ≥0.4 μmol/mg protein | specific activity - |
| assay ≥90% (SDS-PAGE) | assay - |
| Gene Information human ... AKR1C3(8644) | Gene Information human ... AKR1D1(6718) |
| form liquid | form buffered aqueous solution |
| mol wt ~37 kDa | mol wt - |
| shipped in dry ice | shipped in dry ice |
Application
Prostaglandin F synthase (PGF synthase) is a member of the aldo-keto reductase superfamily of proteins which catalyze the conversion of aldehydes and ketones to thier corresponding alcohols. Prostaglandin F synthase is used in cancer research since it is upregulated in many cancers such as breast and prostate cancer. PGF synthase is also used to study kidney and renal cell carcinoma [1].
Biochem/physiol Actions
PGF synthase catalyzes the conversions of 4-androstene-3,17-dione to testosterone, estrone to 17β-estradiol, prostaglandin H2 to PGF2α, and PGD2 to 9α,11β-PGF2. Prostaglandin (PG) F2 is synthesized via three pathways [2].
Other Notes
One unit is defined as the amount of enzyme required to produce 1 μmol of NADP per minute at 37°C in 50 mM KPO4 pH 7.2 containing 250 μM NADPH and 25 μM 9,10-phenanthrenequinone
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Dominika Slonina et al.
Prostaglandins & other lipid mediators, 90(3-4), 69-75 (2009-09-15)
The aim was to study whether bovine myometrial cells have an enzymatic system able to produce prostaglandins (PGs) and whether PGs synthesis is regulated by steroids in a similar manner as endometrial cells. In Experiment 1, immunohistochemical studies localized proteins
Kikuko Watanabe
Prostaglandins & other lipid mediators, 68-69, 401-407 (2002-11-16)
Prostaglandin (PG) F2 is synthesized via three pathways from PGE2, PGD2, or PGH2 by PGE 9-ketoreductase, PGD 11-ketoreductase, or PGH 9-, 11-endoperoxide reductase, respectively. The enzymological and molecular biological properties of these enzymes have been reported in work over the
Mariusz Pawel Kowalewski et al.
Animal reproduction science, 116(1-2), 129-138 (2009-01-24)
In nonpregnant and pregnant dogs the corpora lutea (CL) are the only source of progesterone (P4) which shows an almost identical secretion pattern until the rapid decrease of P4 prior to parturition. For the nonpregnant dog clear evidence has been
Marta Wasielak et al.
Reproduction, fertility, and development, 21(5), 709-717 (2009-06-03)
The present study was conducted to evaluate the effect of the conceptus on uterine prostaglandin-F2alpha (PGF2alpha) and prostaglandin-E2 (PGE2) release and the expression of prostaglandin synthase enzymes during the periimplantation period in the pig. A surgically generated model with conceptuses
R J Phillips et al.
Molecular human reproduction, 17(1), 1-13 (2010-07-03)
Prostaglandins (PGs) are important factors in the physiology of human parturition and the control of uterine contractility. We have characterized the expression of 15 genes from all stages of the PG pathway in human pregnant and non-pregnant (NP) myometrium and
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| F7807-50UG | 04061832729527 |
Filtros activos
Nuestro equipo de científicos tiene experiencia en todas las áreas de investigación: Ciencias de la vida, Ciencia de los materiales, Síntesis química, Cromatografía, Analítica y muchas otras.
Póngase en contacto con el Servicio técnico