E3256
Edrophonium chloride
Sinónimos:
Ethyl(m-hydroxyphenyl)dimethylammonium chloride
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Fórmula empírica (notación de Hill):
C10H16ClNO
Número CAS:
Peso molecular:
201.69
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
204-138-4
MDL number:
Servicio técnico
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Permítanos ayudarleSMILES string
[Cl-].CC[N+](C)(C)c1cccc(O)c1
InChI
1S/C10H15NO.ClH/c1-4-11(2,3)9-6-5-7-10(12)8-9;/h5-8H,4H2,1-3H3;1H
InChI key
BXKDSDJJOVIHMX-UHFFFAOYSA-N
Gene Information
human ... ACHE(43)
Biochem/physiol Actions
Acetycholinesterase inhibitor
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Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Francesco Leonetti et al.
Bioorganic & medicinal chemistry, 16(15), 7450-7456 (2008-07-01)
A number of mono- and bis-quaternary ammonium salts, containing edrophonium-like and coumarin moieties tethered by an appropriate linker, proved to be highly potent and selective dual binding site acetylcholinesterase inhibitors with good selectivity over butyrylcholinesterase. Homobivalent bis-quaternary inhibitors 11 and
Yehonatan Sharabi et al.
Movement disorders : official journal of the Movement Disorder Society, 23(12), 1725-1732 (2008-07-29)
Patients with Parkinson's disease (PD) often have manifestations of autonomic failure. About 40% have neurogenic orthostatic hypotension (NOH), and among PD+NOH patients virtually all have evidence of cardiac sympathetic denervation; however, whether PD+NOH entails extra-cardiac noradrenergic denervation has been less
Yuu Yamazaki et al.
Internal medicine (Tokyo, Japan), 49(1), 69-72 (2010-01-05)
We describe a 52-year-old man with a history of increasing fatigability and gait disturbances that were first attributed to hypothyroidism. On examination, he had bilateral pseudo-internuclear ophthalmoplegia with weakness of adduction and abducting nystagmus. Convergence was also impaired and he