D9069

N-Desmethyltamoxifen HCl

≥98% (HPLC), solid

• Sinónimos: (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548
• Fórmula empírica (notación de Hill): C₂₅H₂₇NO·HCl
• Número CAS: 15917-65-4
• Peso molecular: 393.95
• NACRES: NA.77
• PubChem Substance ID: 329798889
• UNSPSC Code: 12352203
• MDL number: MFCD03423594
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Propiedades

• sterility: non-sterile
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• technique(s): inhibition assay: suitable
• solubility: DMSO: ≥20 mg/mL
• shipped in: ambient
• storage temp.: room temp
• SMILES string: Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3
• InChI: 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
• InChI key: GMLHJWZEYLTNJW-BJFQDICYSA-N

Descripción

Application

N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.

Biochem/physiol Actions

N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.

Features and Benefits

This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Información de seguridad

• pictograms: GHS08,GHS09
• signalword: Danger
• hcodes: H350,H360,H410
• pcodes: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges