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D4025

Dimetridazole

Sinónimos:

1,2-Dimethyl-5-nitroimidazole

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Fórmula empírica (notación de Hill):
C5H7N3O2
Número CAS:
Peso molecular:
141.13
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
209-001-2
Beilstein/REAXYS Number:
130665
MDL number:


form

powder

color

almost white to brownish-yellow

solubility

ethanol: sparingly soluble 96%, H2O: slightly soluble, chloroform: freely soluble, ether: slightly soluble

antibiotic activity spectrum

Gram-negative bacteria, parasites

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

Cc1ncc(n1C)[N+]([O-])=O

InChI

1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3

InChI key

IBXPYPUJPLLOIN-UHFFFAOYSA-N

Application

It is a potential antimicrobial agent against Campylobacter spp. from pigs[1]. It has been used to study antitrichomonad action on Tritrichomonas foetus[2]. Dimetridazole is used to study mechanisms of anti-protozoan nitroimidazole drugs.


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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Harold M J F van der Heijden et al.
Avian pathology : journal of the W.V.P.A, 37(1), 45-50 (2008-01-19)
Histomoniasis is a serious disease in poultry. All chemotherapeutics with known efficacy against its causative agent, Histomonas meleagridis, have been banned from use as prophylactic or therapeutic use in production animals. In a search for possible alternatives, the in vivo
M P Callait et al.
Poultry science, 81(8), 1122-1127 (2002-09-05)
Histomoniasis or blackhead is a life-threatening disease of turkeys that is caused by a flagellated protozoan, Histomonas meleagridis. The development of an assay to measure the sensitivity of drugs traditionally used against this parasite, as reputed to be effective against
K S Warren et al.
Australian veterinary journal, 81(12), 739-741 (2004-04-15)
Cryptosporidiosis is an enteric disease of animals and humans that can be fatal in immunocompromised individuals. There is no known effective treatment for cryptosporidiosis. Bilbies are threatened marsupials and are bred in captivity as part of a recovery program to



Número de artículo de comercio global

SKUGTIN
D4025-100G04061833563922
D4025-1KG04061826718315

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