B174
BIBP 3226
Sinónimos:
N2-(Diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-arginine amide
Iniciar sesión para ver los precios por organización y contrato.
Acerca de este artículo
Fórmula empírica (notación de Hill):
C27H31N5O3
Número CAS:
Peso molecular:
473.57
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
assay
≥95%
solubility
H2O: 1 mg/mL
storage temp.
−20°C
SMILES string
NC(=N)NCCC[C@@H](NC(=O)C(c1ccccc1)c2ccccc2)C(=O)NCc3ccc(O)cc3
InChI
1S/C27H31N5O3/c28-27(29)30-17-7-12-23(25(34)31-18-19-13-15-22(33)16-14-19)32-26(35)24(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-6,8-11,13-16,23-24,33H,7,12,17-18H2,(H,31,34)(H,32,35)(H4,28,29,30)/t23-/m1/s1
InChI key
KUWBXRGRMQZCSS-HSZRJFAPSA-N
Biochem/physiol Actions
Selective non-peptide neuropeptide Y1 (NPY1) receptor antagonist.
Features and Benefits
This compound is featured on the Neuropeptide Y Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Olga Zagorácz et al.
Brain research, 1727, 146563-146563 (2019-11-26)
Even though several of RFamide peptides have been shown to modify memory and learning processes in different species, almost nothing is known regarding cognitive effects of recently discovered neuropeptide QRFP. Considering multiple physiological functions of QRFP, localization of QRFP-synthesizing neurons
Luisa Barreiros et al.
Analytical and bioanalytical chemistry, 412(24), 6625-6632 (2020-07-31)
Neuropeptide Y (NPY) is a peptide widely distributed throughout the body that is involved in various physiological processes, including the regulation of feeding behavior and energy homeostasis. 5-Carbamimidamido-2-(2,2-diphenylacetamido)-N-[(4-hydroxyphenyl)methyl]pentanamide (BIBP 3226) is a selective NPY Y1 receptor antagonist with recognized application
H N Doods et al.
The Journal of pharmacology and experimental therapeutics, 275(1), 136-142 (1995-10-01)
The present study was undertaken to investigate the in vitro and in vivo pharmacological profile of the novel, nonpeptide neuropeptide Y (NPY) Y1-selective antagonist, BIBP 3226 [(R)-N2-(diphenylacetyl)-N-[(4-hydroxyphenyl)methyl]-D-arginine-am ide], and a recently described peptidic structure [Ile-Glu-Pro-Orn-Tyr-Arg-Leu-Arg-Tyr-NH2, cyclic (2,4'), (2',4)-diamide]. BIBP 3226