A2093

Aspirin

meets USP testing specifications

• Sinónimos: Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
• Fórmula lineal: 2-(CH₃CO₂)C₆H₄CO₂H
• Número de CAS: 50-78-2
• Peso molecular: 180.16
• Beilstein: 779271
• Número CE: 200-064-1
• Número MDL: MFCD00002430
• Código UNSPSC: 12352106
• ID de la sustancia en PubChem: 24890623
• NACRES: NA.21

Propiedades

• Agency: USP/NF; meets USP testing specifications
• Nivel de calidad: 200
• formulario: powder or crystals
• mp: 134-136 °C (lit.)
• aplicaciones: pharmaceutical (small molecule)
• cadena SMILES: CC(=O)Oc1ccccc1C(O)=O
• InChI: 1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)
• Clave InChI: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
• Información sobre el gen: human ... ITGA2B(3674) , PTGS1(5742) , PTGS2(5743)

Descripción

Descripción general

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.

Aplicación

Aspirin has been used:

• as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
• to evaluate cell viability of BV-2 microglial cell line
• in morphogenesis assay

Acciones bioquímicas o fisiológicas

Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.

Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Información de seguridad

• Pictogramas: GHS07
• Palabra de señalización: Warning
• Frases de peligro: H302
• Consejos de prudencia: P264 - P270 - P301 + P312 - P501
• Clasificaciones de peligro: Acute Tox. 4 Oral
• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 1
• Punto de inflamabilidad (°F): 482.0 °F
• Punto de inflamabilidad (°C): 250 °C
• Equipo de protección personal: dust mask type N95 (US), Eyeshields, Faceshields, Gloves