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Merck
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64382

Sigma-Aldrich

DL-Methionine methylsulfonium chloride

≥97.0% (AT)

Sinónimos:

(3-Amino-3-carboxypropyl)dimethyl sulfonium chloride, MMS, Methyl-methionine sulphonium chloride, Vitamin U

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About This Item

Fórmula empírica (notación de Hill):
C6H14ClNO2S
Número de CAS:
3493-12-7
Peso molecular:
199.70
Beilstein:
4163617
Número CE:
222-484-4
Número MDL:
MFCD00031700
Código UNSPSC:
12352209
ID de la sustancia en PubChem:
57651981
NACRES:
NA.26

origen biológico

synthetic

Análisis

≥97.0% (AT)

formulario

powder

impurezas

≤0.002% heavy metals

residuo de ign.

≤0.1%

pérdida

≤3% loss on drying

color

colorless to white

pH

4.0-5.5

mp

139-140 °C

solubilidad

H2O: 100 mg/mL, clear, colorless

cadena SMILES

[Cl-].C[S+](C)CCC(N)C(O)=O

InChI

1S/C6H13NO2S.ClH/c1-10(2)4-3-5(7)6(8)9;/h5H,3-4,7H2,1-2H3;1H

Clave InChI

MYGVPKMVGSXPCQ-UHFFFAOYSA-N

Acciones bioquímicas o fisiológicas

DL-Methionine methylsulfonium (DL-MMSC), a racemic mixture, is used to study its mechanism of protection against gastric ulceration. DL-MMSC may also be used as a methionine analogue.
S-Methionine methylsulfonium (SMMS) chloride is a derivative of methionine metabolism in some plants. SMMS has potent therapeutic effects on gastrointestinal ulceration potentially via its ability to promote dermal fibroblast migration and growth.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Takafumi Ichikawa et al.
Journal of gastroenterology and hepatology, 24(3), 488-492 (2009-01-30)
In Japan, peptic ulcer disease (PUD) is treated clinically with a combination of a mucosal protectant and acid suppressants, but there is scant information regarding the effects of these drugs on normal gastric mucus cells. In the present study, the
A S Salim
Journal of pharmaceutical sciences, 81(1), 70-73 (1992-01-01)
One milliliter of 1, 2, or 5% DL-cysteine (cysteine) or DL-methionine methylsulfonium chloride (MMSC) was instilled into the rat stomach 1, 24, and 48 h after giving ethanol (1 mL of 40% solution) by gavage. One hour following the administration
Kinuyo Matsumoto et al.
Metallomics : integrated biometal science, 3(7), 683-685 (2011-06-28)
The insulinomimetic activity of a Zn(ii) complex is reported. The effects of the Zn(ii) complex with ascorbic acid (Vitamin C; VC), methylmethionine sulfonium chloride (Vitamin U; VU) and l-carnitine were assessed in diet-induced metabolic syndrome model rats. Zn(VU)(2)Cl(2) and Zn(VC)Cl(2)
A S Salim
Pharmacology, 46(5), 281-288 (1993-05-01)
This prospective randomized double-blind controlled study investigated whether sulphydryl-containing agents protect against the recurrence of duodenal ulceration. To this end, DL-cysteine (200 mg 4 times daily) and DL-methionine-methyl sulphonium chloride (MMSC, 500 mg 4 times daily) were administered orally. Three
Dharmendra Kumar et al.
Bioresource technology, 96(3), 287-294 (2004-10-12)
The production of methionine by submerged fermentation using a mutant strain of Corynebacterium lilium was studied to determine suitable conditions for obtaining high productivity. The mutant strain resistant to the methionine analogues ethionine, norleucine, methionine sulfoxide and methionine methylsulfonium chloride
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