51290

Hemoglobin from bovine blood

lyophilized, 2×cryst., ≥90% (SDS-PAGE), powder

• Sinónimos: Bovine hemoglobin, Hb, Methemoglobin
• Número CAS: 9008-02-0
• UNSPSC Code: 12352202
• MDL number: MFCD00131282
• eCl@ss: 42030116
• Form: powder
• Assay: ≥90% (SDS-PAGE)
• Biological source: bovine blood
• Mol wt: M_r ~64500

Propiedades

• biological source: bovine blood
• Quality Segment: 100
• assay: ≥90% (SDS-PAGE)
• form: powder
• quality: 2×cryst., lyophilized
• mol wt: M_r ~64500
• technique(s): UV/Vis spectroscopy: suitable
• impurities: salt, none detected, ~0.3% Fe
• loss: ≤8% loss on drying
• UniProt accession no.: P01966, P02070, P02081, P06642, P06643
• shipped in: ambient
• storage temp.: 2-8°C
• Gene Information: cow ... HBA1(281221), HBB(280813), HBE2(513240), HBE4(513108), HBG(511735), alpha globin(512439)

Descripción

General description

Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC. [1]

Application

The solubility of α-elastin has been applied to construction of elastin-mimetic biomaterials.

Biochem/physiol Actions

Oxygen transporter, NO scavenger

Oxygen transporter. The Fe²⁺/Fe³⁺ balance is a physiological indicator of blood oxygenation; deoxygenated hemoglobin accessorizes a feedback loop by reducing nitrite to NO, a vasodilator which enhances blood flow to oxygen-deprived tissues.

Other Notes

Sales restrictions may apply

Review: Oxygen carrier proteins

Disclaimer

Since native hemoglobin is readily oxidized in air, these preparations may be predominantly methemoglobin.

Información de seguridad

• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)