vial of 0.1 mL (concentrate (490M-14)), vial of 0.1 mL (concentrate (490M-14-RUO) Research Use Only), vial of 0.5 mL (concentrate (490M-15)), vial of 1.0 mL (concentrate (490M-16)), vial of 1.0 mL (concentrate (490M-16-RUO) Research Use Only), vial of 1.0 mL (pre-dilute (490M-17-RUO) Research Use Only), vial of 1.0 mL (pre-dilute ready-to-use (490M-17)), vial of 7.0 mL (pre-dilute ready-to-use (490M-18)), vial of 7.0 mL (pre-dilute ready-to-use (490M-18-RUO) Research Use Only)
Tyrosine Hydroxylase (TYH) is the rate-limiting enzyme of catecholamine biosynthesiss. TYH uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-DOPA, a precursor to dopamine. Anti-TYH is sensitive and specific for peripheral neuroblastic tumors in the differential diagnosis from other tumors of childhood and shows high diagnostic utility. Anti-TYH has been shown to positively label all pheochromocytomas and sympathetic paragangliomas, and thus aids in differentiating them from their histologic mimics such as adrenocortical neoplasms.
Physical form
Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.
