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306M-2

NSE (MRQ-55) Mouse Monoclonal Antibody

Name: NSE (MRQ-55) Mouse Monoclonal Antibody
Brand: SIGMA

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Acerca de este artículo

NACRES:

NA.41

UNSPSC Code:

12352203

Conjugate:

unconjugated

Clone:

MRQ-55, monoclonal

Application:

IHC (p)

Citations:

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Servicio técnico

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Propiedades

biological source

mouse

Quality Level

100, 500

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

MRQ-55, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (306M-24), vial of 0.5 mL concentrate (306M-25), bottle of 1.0 mL predilute (306M-27), vial of 1.0 mL concentrate (306M-26), bottle of 7.0 mL predilute (306M-28)

manufacturer/tradename

Cell Marque^®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

isotype

IgG2b

control

appendix/colon, schwannoma

shipped in

wet ice

storage temp.

2-8°C

visualization

cytoplasmic

Gene Information

human ... ENO2(2026)

Descripción

General description

Neuron-specific enolase (NSE) is a glycolytic isoenzyme of the enolase gamma-gamma dimerselectively detected in neurons, peripheral nerves, some neuroendocrine cells, and tumors.NSE immunoreactivity is also observed, to a lesser extent, in smooth muscle tissue. Anti-NSEis often used to visualize peripheral nerves and for the identification of neuroendocrinedifferentiation.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note

IVD

RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

NSE Positive Control Slides, Product No. 306S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

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Este artículo	AC-0350	AC-0350A	SAB4200571
Sigma-Aldrich 306M-2 NSE (MRQ-55) Mouse Monoclonal Antibody	Sigma-Aldrich AC-0350 Neuron-specific enolase (NSE) (EP319) Rabbit Monoclonal Primary Antibody	Sigma-Aldrich AC-0350A Neuron-specific enolase (NSE) (EP319) Rabbit Monoclonal Primary Antibody	Sigma-Aldrich SAB4200571 Anti-Neuron-Specific Enolase (NSE), Mouse monoclonal
clone MRQ-55, monoclonal	clone monoclonal	clone monoclonal	clone NSE-P1, monoclonal
conjugate unconjugated	conjugate -	conjugate -	conjugate unconjugated
species reactivity human	species reactivity -	species reactivity -	species reactivity human, rat, mouse
biological source mouse	biological source rabbit	biological source rabbit	biological source mouse
antibody form culture supernatant	antibody form Ig fraction of antiserum	antibody form Ig fraction of antiserum	antibody form purified from hybridoma cell culture
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. −20°C

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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Neuroproliferation in the mucosa is a feature of coeliac disease and Crohn's disease.

N Leonard et al.

Gut, 37(6), 763-765 (1995-12-01)

The pathogenesis of villous damage in coeliac disease is unknown. Change to the delicate neuromuscular core may be significant and this study stained various categories of coeliac disease and controls with neuron-specific enolase (NSE) to examine neurofilaments in the mucosa.

Criteria for the diagnosis of primary endocrine carcinoma of the skin (Merkel cell carcinoma). A histological, immunohistochemical and ultrastructural study of 13 cases.

A S Leong et al.

Pathology, 18(4), 393-399 (1986-10-01)

Thirteen cases of primary endocrine carcinoma of the skin (Merkel cell carcinoma) were reviewed with the aim of defining the morphological, immunohistochemical and ultrastructural criteria for diagnosis. The tumour cells were characterized by their scanty cytoplasm, generally small uniform nuclei

Neuron-specific enolase.

E H Cooper

The International journal of biological markers, 9(4), 205-210 (1994-10-01)

The clinical value of neuron-specific enolase as a marker is small cell lung cancer, neuroblastoma, melanoma and seminoma has been reviewed. The role of serum and cerebrospinal NSE in benign and malignant disease of the central nervous system is discussed.

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Número de artículo de comercio global

SKU	GTIN
306M-25	0841683120995
306M-26	0841683134640
306M-27	0841683121008
306M-28	0841683121015
306M-24	0841683120988

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