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A7409

Sigma-Aldrich

Seroalbúmina bovina solution

35% in 0.85% sodium chloride, aseptically filled

Sinónimos:

Albúmina solution from bovine serum, Disolución BSA

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10 ML
177,00 €
50 ML
324,00 €
1 L
2030,00 €

177,00 €


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10 ML
177,00 €
50 ML
324,00 €
1 L
2030,00 €

About This Item

Número de CAS:
Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.27

177,00 €


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origen biológico

bovine

Nivel de calidad

descripción

contains no preservative

esterilidad

aseptically filled

Formulario

solution

purificado por

heat shock fractionation

origen

USA origin

concentración

33.0-37.4% protein (biuret)
35% in 0.85% sodium chloride

técnicas

microbiological culture: suitable

Nº de acceso UniProt

temp. de almacenamiento

2-8°C

Información sobre el gen

bovine ... ALB(280717)

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Descripción general

Albumin belongs to the four-member albumin superfamily.[1] It is a major protein in the circulating blood.[2] Albumin has a helical structure with three domains that form a heart-like shape.[1]

Aplicación

Bovine Serum Albumin solution has been used:
  • to block protein-coated well plates in enzyme-linked immunosorbent assay (ELISA) for immunoreactivity and cross-reactivity studies in the production of monoclonal antibodies (mAbs)[3]
  • to prepare primary antibody solution for peroxidases staining[4]
  • as a supplement for in vitro cultivation of Borrelia strains[4]

Acciones bioquímicas o fisiológicas

Bovine serum albumin (BSA) serves as a protein supplement for cell culture media.[5] BSA acts as a transport carrier for drugs, and it is commonly used to study the protein-drug interactions. Furthermore, it is known for its ability to interact with several aromatic and hydrophobic molecules of the bloodstream.[6]

Código de clase de almacenamiento

10 - Combustible liquids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves


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Bovine serum albumin
Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, 1045 null
Fatai S Oladunni et al.
Journal of virological methods, 290, 114084-114084 (2021-01-30)
The use of monoclonal neutralizing antibodies (mNAbs) is being actively pursued as a viable intervention for the treatment of Severe Acute Respiratory Syndrome CoV-2 (SARS-CoV-2) infection and associated coronavirus disease 2019 (COVID-19). While highly potent mNAbs have great therapeutic potential
The NMR tube bioreactor
Methods in Enzymology, 71-101 null
Aina Segués et al.
Journal of immunological methods, 499, 113173-113173 (2021-10-27)
Tumor necrosis factor receptor 2 (TNFR2) has gained much research interest in recent years because of its potential pivotal role in autoimmune disease and cancer. However, its function in regulating different immune cells is not well understood. There is a
Paul A Wilson et al.
PloS one, 16(10), e0258316-e0258316 (2021-10-22)
RORγt is an isoform of RORC, preferentially expressed in Th17 cells, that functions as a critical regulator of type 3 immunity. As murine Th17-driven inflammatory disease models were greatly diminished in RORC knock-out mice, this receptor was prioritised as an

Preguntas

  1. Is the BSA cat. A7409 suitable for MACS buffer used for T cell separation? Separated cells would be cultured for around 2 weeks

    1 respuesta
    1. This product has not been tested for suitability in this application. While it is aseptically prepared, this product is not tested for sterility.

      See product A7979 for the sterile, cell culture tested BSA solution that may be more suitable: https://www.sigmaaldrich.com/product/sigma/a7979

      In addition, see product A9418 to review another cell culture tested product that is cited for use in MACS buffer: https://www.sigmaaldrich.com/product/sigma/a9418

      A link to this publication is below:
      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059065/

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