Seleccione un Tamaño
| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|---|---|---|
| 50 μL | Póngase en contacto con nuestro Servicio de Atención al Cliente para disponibilidad | 415,00 € |
Acerca de este artículo
415,00 €
biological source
rat
Quality Level
clone
monoclonal
species reactivity
human
technique(s)
ChIP: suitable, flow cytometry: suitable, western blot: suitable
General description
Immunogen
Application
Chromatin Immunoprecipitation Analysis
Analysis Note
Western Blotting Analysis: A 1:20,000 dilution of this antibody detected TEL-AML1 fusion induction in 2.5 ug lysate from mifepristone-treated murine BA/F3 cells expressing inducible TEL-AML1 fusion.
Other Notes
1 of 1
Este artículo | |||
|---|---|---|---|
| clone monoclonal | clone 3B10, monoclonal | clone polyclonal | clone polyclonal |
| biological source rat | biological source mouse | biological source mouse | biological source rabbit |
| species reactivity human | species reactivity human | species reactivity human | species reactivity human |
| technique(s) ChIP: suitable, western blot: suitable, flow cytometry: suitable | technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL | technique(s) indirect immunofluorescence: suitable, western blot: 1 μg/mL | technique(s) ChIP: 1-10 μg (per reaction), immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:200-1:500 |
| Quality Level 300 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.
Contenido relacionado
A major focus of breast cancer research is to understand the mechanisms responsible for disease progression and drug resistance. Toward that end, it has been found that approximately two thirds of all human breast carcinomas overexpress the Estrogen Receptor α (ERα) protein and it remains the primary pharmacological target for endocrine therapy1,2. The normal cellular function of ERα is as a transcription factor that mediates a wide variety of physiological processes, many of which are dependent upon phosphorylation of the receptor at specific amino acid residues3,4. Indeed, ERα is known to be phosphorylated at a multitude of different sites, yet how these all correlate to disease remains unclear5. Here, we interrogated multiple sites of ERα for phosphorylation status by screening an extensive panel of different breast cancer patient samples and other non-breast cancer tissue microarray (TMA) slide samples to determine their relevance to disease.
Historically chromatin was considered to contain only DNA, histones, non-histone proteins and transiently associated mRNAs. While this remains true, current data suggest that a variety of non-coding RNAs (e.g. long non-coding RNAs, enhancer RNAs and even miRNAs) also associate with chromatin and serve regulatory functions.
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| MABE1007 | 04055977168259 |



