ABC327

Anti-PD-L2 Antibody

from rabbit, purified by affinity chromatography

• Sinónimos: Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273
• Código UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Propiedades

• origen biológico: rabbit
• Nivel de calidad: 100
• forma del anticuerpo: affinity isolated antibody
• tipo de anticuerpo: primary antibodies
• clon: polyclonal
• purificado por: affinity chromatography
• reactividad de especies: human, mouse
• técnicas: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• Nº de acceso UniProt: Q9BQ51
• Condiciones de envío: wet ice
• modificación del objetivo postraduccional: unmodified
• Información sobre el gen: human ... PDCD1LG2(80380)

Descripción

Descripción general

Programmed cell death ligand 2 (PD-L2, PD-1 ligand 2, PDCD1 ligand 2), also known as Butyrophilin B7-DC (B7-DC), is a member of the BTN/MOG family and immunoglobulin superfamily which is thought to act as a negative regulator of T cell activation. PD-L2 may play a role in stimulating an immunogenic response through an alternative receptor from PD-1. PD-L2 is highly expressed in heart, placenta, pancreas, lung, and liver and weakly expressed in spleen, lymph nodes, and thymus.

Especificidad

This antibody only recognizes the largest isoform at ~31 kDa.

Inmunógeno

KLH-conjugated linear peptide corresponding to human PD-L2.

Aplicación

Anti-PD-L2 Antibody is a highly specific rabbit polyclonal antibody, that targets Programmed cell death 1 ligand 1 & has been tested in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PD-L2 in mouse brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected PD-L2 in mouse brain cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Calidad

Evaluated by Western Blotting in Raji cell lysate

Western Blotting Analysis: 2 µg/mL of this antibody detected PD-L2 in 15 µg of Raji cell lysate.

Descripción de destino

~31 kDa observed. Uniprot describes 2 isoforms at ~21 kDa and one isoform at ~31 kDa Uncharacterized bands may appear in some lysate(s).

Forma física

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Almacenamiento y estabilidad

Stable for 1 year at 2-8°C from date of receipt.

Nota de análisis

Control
Raji cell lysate

Otras notas

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Cláusula de descargo de responsabilidad

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Clase de riesgo para el agua (WGK): WGK 2
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable