494459

n-Octyl-β-D-glucopyranoside

CAS 29836-26-8 is a non-ionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles.

• Sinónimos: n-Octyl-β-D-glucopyranoside, OG, n-Octylglucoside
• Fórmula empírica (notación de Hill): C₁₄H₂₈O₆
• Número de CAS: 29836-26-8
• Peso molecular: 292.37
• Número MDL: MFCD00063288
• Código UNSPSC: 12161902
• NACRES: NA.21

Propiedades

• Nivel de calidad: 300
• Análisis: ≥98% (HPLC)
• formulario: solid
• fabricante / nombre comercial: Calbiochem^®
• condiciones de almacenamiento: OK to freeze; desiccated (hygroscopic)
• número de agregación: 84
• impurezas: ≤0.05% n-octanol; ≤35 mg/dL glucose
• color: white
• CMC: 20 - 25 mM
• solubilidad: water: 100 mg/mL
• Condiciones de envío: ambient
• temp. de almacenamiento: 15-25°C
• InChI: 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
• Clave InChI: HEGSGKPQLMEBJL-RKQHYHRCSA-N

Descripción

Descripción general

Absorbance (10%, H₂O, 260 nm):≤0.3.

Non–ionic detergent intended for solubilizing membrane–bound proteins in their native state and for the preparation of lipid vesicles. Its well–defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Nonionic detergent intended for solubilizing membrane-bound proteins in their native state and for the preparation of lipid vesicles. Its well-defined chemical structure, small uniform micelles, and high water solubility make it superior to most other nonionic detergents for membrane solubilization. Because of its high critical micelle concentration (20-25 mM), it has the additional advantage of being removed easily by dialysis when compared to bile salts. Aggregation number: 84.

Aplicación

• Tube-gel digestion: a novel proteomic approach for high throughput analysis of membrane proteins.: This article introduces a new method for analyzing membrane proteins using tube-gel digestion, which employs n-Octyl-β-D-glucopyranoside for effective solubilization of membrane proteins. This approach enhances the throughput and efficiency of proteomic analyses (Lu et al., 2005).


• Mixed micellization of a nonionic-cationic surfactant system constituted by n-octyl-beta-D-glucopyranoside/dodecyltrimethylammonium bromide/H2O.: The study explores the micellization behavior of a nonionic-cationic surfactant system involving n-Octyl-β-D-glucopyranoside and its interactions. The findings are significant for understanding surfactant properties and applications in biochemical processes (del Burgo et al., 2004).

Advertencia

Toxicity: Standard Handling (A)

Reconstitución

Following reconstitution, store in the refrigerator (4°C), under sterile conditions. Aqueous stock solutions are stable for up to 3 months at 4°C. Solutions are susceptible to hydrolysis (especially acidic solutions) and enzymatic hydrolysis.

Otras notas

Hoshino, T., et al. 1992. J. Biol. Chem.267, 21313.
Levy, D., et al. 1992. Biochim. Biophys. Acta1107, 283.
Nunn, R.S., et al. 1992. J. Mol. Biol.228, 1259.
Lorber, B., et al. 1990. Biochim. Biophys. Acta1023, 254.
Jopski, B., et al. 1989. Biochim. Biophys. Acta978, 79.
Camm, E.L., et al. 1981. Plant Physiol.67, 1061.
Gould, R.J., et al. 1981. Biochemistry20, 6776.

Información legal

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Información de seguridad

• Código de clase de almacenamiento: 13 - Non Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable