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Merck

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07-692

Anti-Sar1 Antibody

Upstate®, from rabbit

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eCl@ss:
32160702
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
11


biological source

rabbit

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

monkey, mouse, rat, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... ROR1(4919)

General description

Mr 21kDa

Immunogen

KLH-conjugated, synthetic peptide corresponding to amino acids 46-62 (CKDDRLGQHVPTLHPTSE) of human Sar1 (a and b isoforms), with an N-terminal cysteine added for conjugation purposes

Application

Detect Sar1 using this Anti-Sar1 Antibody validated for use in WB.
Research Category
Signaling
Research Sub Category
G-proteins

Kinases & Phosphatases

Biochem/physiol Actions

Sar1

Physical form

Format: Purified
Protein A purified

Preparation Note

stable 2 years at -20°C from date of shipment

Analysis Note

Control
Positive Antigen Control: Catalog #12-305, 3T3/A31 lysate. Add 2.5 μL of 2-mercapto-ethanol/100 μL of lysate and boil for 5 minutes to reduce the preparation. Load 20 μg of reduced lysate per lane for minigels.
routinely evaluated by immunoblot on RIPA lysates from 3T3/A31 cells

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Clase de almacenamiento

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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François-Xavier Campbell-Valois et al.
Molecular & cellular proteomics : MCP, 11(7), M111-M111 (2012-03-20)
Phagosomes, by killing and degrading pathogens for antigen presentation, are organelles implicated in key aspects of innate and adaptive immunity. Although it has been well established that phagosomes consist of membranes from the plasma membrane, endosomes, and lysosomes, the notion
Xue-Hai Liang et al.
Nucleic acids research, 46(19), 10225-10245 (2018-09-22)
RNase H1-dependent, phosphorothioate-modified antisense oligonucleotides (PS-ASOs) can enter cells through endocytic pathways and need to be released from the membrane-enclosed organelles, a limiting step for antisense activity. Accumulating evidence has suggested that productive PS-ASO release mainly occurs from late endosomes
A structural view of the COPII vesicle coat.
Bickford, Lincoln C, et al.
Current Opinion in Structural Biology, 14, 147-153 (2004)



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