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07-532

Anti-phospho-PKR (Thr446) Antibody

Upstate®, from rabbit

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Tamaño de envaseSKUDisponibilidadPrecio
100 μg
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399,00 €

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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
WB
Citations:
10

399,00 €


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biological source

rabbit

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pThr446)

Gene Information

human ... EIF2AK2(5610)

General description

68 kDa

Immunogen

Peptide corresponding to amino acids surrounding Thr446 of human PKR.

Application

Anti-phospho-PKR (Thr446) Antibody is an antibody against phospho-PKR (Thr446) for use in WB.
Research Category
Signaling
Research Sub Category
Cytoskeletal Signaling

Biochem/physiol Actions

phospho-PKR

Physical form

0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein A purified

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot in RIPA lysates from HeLa cells that had been stimulated with IFN alpha overnight followed by treatment with calyculin A for 15 minutes

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Este artículo
07-88607-78907-888
clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity purified immunoglobulin

antibody form

affinity purified immunoglobulin

species reactivity

human

species reactivity

mouse, human

species reactivity

human

species reactivity

mouse, human

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

Gene Information

human ... EIF2AK2(5610)

Gene Information

human ... EIF2AK2(5610)
mouse ... Eif2Ak2(19106)

Gene Information

human ... AKT1(207)

Gene Information

human ... AKT1S1(84335)
mouse ... Akt1S1(67605)


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Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 1



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X Saelens et al.
The Journal of biological chemistry, 276(45), 41620-41628 (2001-09-14)
The protein kinase PKR is a major player in the cellular antiviral response, acting mainly by phosphorylation of the alpha-subunit of the eukaryotic translation initiation factor 2 (eIF2-alpha) to block de novo protein synthesis. PKR activation requires binding of double-stranded
Ka-Chun Suen et al.
The Journal of biological chemistry, 278(50), 49819-49827 (2003-09-17)
One of the hallmarks of Alzheimer's disease is extracellular accumulation of senile plaques composed primarily of aggregated beta-amyloid (Abeta) peptide. Treatment of cultured neurons with Abeta peptide induces neuronal death in which apoptosis is suggested to be one of the
Dario Paolo et al.
Plants (Basel, Switzerland), 10(2) (2021-01-28)
Seed size is the result of complex molecular networks controlling the development of the seed coat (of maternal origin) and the two fertilization products, the embryo and the endosperm. In this study we characterized the role of Arabidopsis thaliana MADS-domain



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SKUGTIN
07-53204053252513077

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