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P148

4α-Phorbol 12-myristate 13-acetate

solid, ≥95% (TLC)

Sinónimos:

4α-PMA

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Tamaño de envaseSKUDisponibilidadPrecio
1 mg
Comprobar disponibilidad del carrito
MXP 6,472.00

Acerca de este artículo

Fórmula empírica (notación de Hill):
C36H56O8
Número CAS:
63597-44-4
Peso molecular:
616.83
NACRES:
NA.77
PubChem Substance ID:
24898203
UNSPSC Code:
12352211
MDL number:
MFCD00153860
Assay:
≥95% (TLC)
Form:
solid
Quality level:
100

MXP 6,472.00

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Quality Level

100

assay

≥95% (TLC)

form

solid

color

white

solubility

H2O: ~2 μM, DMSO: soluble, ethanol: soluble

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCCC(=O)O[C@@H]1[C@@H](C)[C@@]2(O)C(C=C(CO)C[C@]3(O)C2C=C(C)C3=O)C4C(C)(C)[C@]14OC(C)=O

InChI

1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34+,35-,36-/m1/s1

InChI key

PHEDXBVPIONUQT-LQLWEASQSA-N

General description

Though having aqueous solubility, it is recommended that this compound first be dissolved in a water miscible organic solvent before dilution to working concentrations in aqueous media.

Biochem/physiol Actions

Negative control for phorbol ester activation of protein kinase C.

Packaging

Sealed glass ampule.

Disclaimer

Photosensitive

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Este artículo
P8139C2020P1585
4α-Phorbol 12-myristate 13-acetate solid, ≥95% (TLC)

Sigma-Aldrich

P148

4α-Phorbol 12-myristate 13-acetate

Phorbol 12-myristate 13-acetate ≥99% (TLC), film or powder

Sigma-Aldrich

P8139

Phorbol 12-myristate 13-acetate

α-Cyano-4-hydroxycinnamic acid ≥98% (TLC), powder

Sigma-Aldrich

C2020

α-Cyano-4-hydroxycinnamic acid

PMA for use in molecular biology applications, ≥99% (HPLC), Molecular Biology

Sigma-Aldrich

P1585

PMA

form

solid

form

film or powder

form

powder

form

(Lyophilisate)

assay

≥95% (TLC)

assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥99% (HPLC)

Quality Level

100

Quality Level

200

Quality Level

300

Quality Level

200

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

H2O: ~2 μM, ethanol: soluble, DMSO: soluble

solubility

DMSO: soluble, ethanol: soluble (Dissolve in water-miscible organic solvent prior to preparing aqueous solutions.)

solubility

H2O: slightly soluble, methanol: water: soluble, polar organic solvents: soluble

solubility

DMSO: soluble (DMSO solutions can be stored dark at −20 °C for at least six months.), ethanol: soluble (Dissolve in water-miscible organic solvent prior to preparing aqueous solutions)

color

white

color

-

color

yellow

color

-

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
MKCR3206
MKCQ1294
MKCN8591
MKCL0558
MKCG5400

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S M Fischer et al.
Cancer research, 51(3), 850-856 (1991-02-01)
There is substantial evidence that the tumor promoter 4 beta-12-O-tetradecanoylphorbol-13-acetate (TPA) elicits enhanced arachidonic acid release and its metabolism to prostaglandins and lipoxygenase products in many cell types. The goal of this study was to determine whether 4 alpha-12-O-tetradecanoylphorbol-13-acetate (4
Shirley A Cotton et al.
Kidney international, 61(1), 61-67 (2002-01-12)
Significant variability exists in the outcome of renal parenchymal inflammation following urinary tract infection (UTI) in childhood as some children experience renal parenchymal scarring (RPS) while others do not scar. Since TGF-beta1 is pro-fibrotic, we examined the role of this
Hussein Ghamlouch et al.
PloS one, 8(3), e60370-e60370 (2013-04-05)
B-chronic lymphocytic leukemia (B-CLL), the most common human leukemia, is characterized by predominantly non-dividing malignant mature CD5+ B lymphocytes with an apoptosis defect. Various microenvironmental stimuli confer a growth advantage on these leukemic cells and extend their survival in vivo.
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Número de artículo de comercio global

SKUGTIN
P148-1MG04061834355052

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