1619006

Spironolactone

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 4-Pregnen-21-oic acid-17α-ol-3-one-7α-thiol γ-lactone 7-acetate, 7α-(Acetylthio)-17α-hydroxy-3-oxopregn-4-ene-21-carboxylic acid γ-lactone
• Fórmula empírica (notación de Hill): C₂₄H₃₂O₄S
• Número CAS: 52-01-7
• Peso molecular: 416.57
• NACRES: NA.24
• PubChem Substance ID: 329751140
• UNSPSC Code: 41116107
• MDL number: MFCD00082250

Propiedades

• grade: pharmaceutical primary standard
• API family: spironolactone
• manufacturer/tradename: USP
• mp: 207-208 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]45CCC(=O)O5)[C@H]13
• InChI: 1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1
• InChI key: LXMSZDCAJNLERA-ZHYRCANASA-N
• Gene Information: human ... NR3C2(4306)

Descripción

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Spironolactone USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Spironolactone and Hydrochlorothiazide Compounded Oral Suspension
• Spironolactone and Hydrochlorothiazide Tablets
• Spironolactone Compounded Oral Suspension
• Spironolactone Compounded Oral Suspension, Veterinary
• Spironolactone Tablets

Biochem/physiol Actions

Spironolactone is a competitive aldosterone receptor antagonist. Used as potassium sparing diuretic.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Información de seguridad

• pictograms: GHS08
• signalword: Danger
• hcodes: H351,H360FD,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 2 - Repr. 1B - STOT RE 2
• Clase de almacenamiento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable