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Documentos

1012032

USP

Actein

United States Pharmacopeia (USP) Reference Standard

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Shengmating

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About This Item

Fórmula empírica (notación de Hill):
C37H56O11
Número de CAS:
18642-44-9
Peso molecular:
676.83
MDL number:
MFCD25371991
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

actein

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[C@@H]1C[C@@]2([C@H]3[C@@](O3)(C)[C@@H](O)O2)O[C@]4([H])[C@@]1([H])[C@]([C@H](OC(C)=O)C[C@]5(C6)[C@@]7([H])CC[C@]8([H])[C@]56CC[C@H](O[C@]9([H])OC[C@@H](O)[C@H](O)[C@H]9O)C8(C)C)(C)[C@@]7(C)C4

InChI

1S/C35H54O9/c1-17-13-35(27-32(6,43-27)28(39)44-35)42-19-14-31(5)21-8-7-20-29(2,3)22(41-26-25(38)24(37)18(36)15-40-26)9-10-33(20)16-34(21,33)12-11-30(31,4)23(17)19/h17-28,36-39H,7-16H2,1-6H3/t17-,18-,19+,20+,21+,22?,23+,24+,25-,26+,27+,28?,30-,31+,32-,33-,34+,35?/m1/s1

InChI key

RKNTVINERUAWJC-LXVMFROXSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Actein USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Black Cohosh
  • Black Cohosh Fluidextract
  • Black Cohosh Tablets
  • Powdered Black Cohosh
  • Powdered Black Cohosh Extract

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

Referencia del producto
Descripción
Precios

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Linda Saxe Einbond et al.
Anticancer research, 27(2), 697-712 (2007-05-01)
Previous studies indicate that specific extracts and the pure triterpene glycoside actein obtained from black cohosh inhibit growth of human breast cancer cells. Our aim is to identify alterations in gene expression induced by treatment with a methanolic extract (MeOH)
M Koeda et al.
Chemical & pharmaceutical bulletin, 43(5), 771-776 (1995-05-01)
Three new cyclolanostanol xylosides were isolated from a batch of commercial Cimicifuga Rhizome, cimicifugoside H-1 (1), C35H52O9, mp 260-262 degrees C, [alpha]D -43.5 degrees, cimicifugoside H-2 (2), C35H54O10, mp 227-229 degrees C, [alpha]D -38.8 degrees, and cimicifugoside H-5 (3), C35H52O10
Linda Saxe Einbond et al.
International journal of cancer, 121(9), 2073-2083 (2007-07-11)
Previous studies indicate that the triterpene glycoside actein from the herb black cohosh inhibits growth of human breast cancer cells. This study seeks to identify genes altered in human breast cancer cells by treatment with actein, using gene expression analysis.
Linda Saxe Einbond et al.
Biochemical and biophysical research communications, 375(4), 608-613 (2008-08-30)
The Na+K+-ATPase is a known target of cardiac glycosides such as digitoxin and ouabain. We determined that the enzyme also is a target of the structurally-related triterpene glycoside actein, present in the herb black cohosh. Actein's inhibition of Na+-K+-ATPase activity
Linda Saxe Einbond et al.
Planta medica, 72(13), 1200-1206 (2006-09-22)
The purpose of this study was to determine whether the triterpene glycosides present in black cohosh enhance the growth inhibitory effects of specific breast cancer chemotherapy agents. Black cohosh roots and rhizomes were extracted with methanol (MeOH)/water (H (2)O) and
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