Saltar al contenido
Merck

Documentos clave

Ver Toda la documentación

Saltar a

E1279

Enoximone

solid

Sinónimos:

1,3-Dihydro-4-methyl-5-(4-methylthiobenzoyl)-2H-imidazol-2-one

Iniciar sesión para ver los precios por organización y contrato.

Seleccione un Tamaño

Cambiar Vistas
Tamaño de envaseSKUDisponibilidadPrecio
10 mg
Comprobar disponibilidad del carrito
MXP 4,971.00
MXP 4,225.35

Acerca de este artículo

Fórmula empírica (notación de Hill):
C12H12N2O2S
Número CAS:
77671-31-9
Peso molecular:
248.30
NACRES:
NA.77
PubChem Substance ID:
24278408
UNSPSC Code:
41106305
MDL number:
MFCD00867130
Form:
solid
Quality level:
100

MXP 4,225.35

Precio de catálogoMXP 4,971.00Ahorre 15 %
Promoción solo por Internet
Comprobar disponibilidad del carrito
​
Solicite una orden a granel
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarle

form

solid

Quality Level

100

color

light yellow

solubility

DMSO: soluble 28 mg/mL

SMILES string

CSc1ccc(cc1)C(=O)C2=C(C)NC(=O)N2

InChI

1S/C12H12N2O2S/c1-7-10(14-12(16)13-7)11(15)8-3-5-9(17-2)6-4-8/h3-6H,1-2H3,(H2,13,14,16)

InChI key

ZJKNESGOIKRXQY-UHFFFAOYSA-N

Gene Information

human ... PDE3A(5139), PDE3B(5140)

Biochem/physiol Actions

Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE. Increased cAMP results in enhanced contractility of the heart.
Selective phosphodiesterase III (PDE3) inhibitor. Prevents the degradation of cAMP by PDE.

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Comparar elementos similares

Ver comparación completa

Mostrar Diferencias

1 of 1

Este artículo
D9190S5321O9387
Enoximone solid

Sigma-Aldrich

E1279

Enoximone

DCEBIO ≥98% (HPLC), solid

Sigma-Aldrich

D9190

DCEBIO

S15535 ≥98% (HPLC), solid

Sigma-Aldrich

S5321

S15535

Oxatomide ≥99%

Sigma-Aldrich

O9387

Oxatomide

form

solid

form

solid

form

solid

form

powder

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

solubility

DMSO: soluble 28 mg/mL

solubility

DMSO: >10 mg/mL

solubility

DMSO: ~6 mg/mL, H2O: insoluble

solubility

DMSO: soluble, ethanol: soluble

color

light yellow

color

white to off-white

color

white

color

white

Gene Information

human ... PDE3A(5139), PDE3B(5140)

Gene Information

human ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)

Gene Information

-

Gene Information

human ... DRD3(1814)

Clase de almacenamiento

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number
0000239177
0000239177
0000177485
0000177485
0000100763

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

Busque por un COA

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos

Contenido relacionado

Discover Bioactive Molecules for Nucleotides

Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.

Celltransmissions Newsletter
Stijn Schauvliege et al.
Veterinary anaesthesia and analgesia, 35(4), 306-318 (2009-06-16)
To evaluate the combined effects of enoximone and dobutamine on the cardiovascular system and respiratory gas exchange in isoflurane-anaesthetized ponies. Prospective, randomized, experimental study. Six ponies (286 +/- 52 kg), aged 5.0 +/- 1.6 years. After sedation (romifidine 80 microg
D Trenk et al.
Zeitschrift fur Kardiologie, 83 Suppl 2, 7-14 (1994-01-01)
Enoximone is an imidazole derivative which proved to be a selective inhibitor of the isoenzymes III/IV of the cAMP-specific phosphodiesterase. It has been shown in various experimental models that the drug exerts both positive inotropic and vasodilating properties which can
E Jähnchen et al.
Zeitschrift fur Kardiologie, 80 Suppl 4, 21-26 (1991-01-01)
Enoximone belongs to the imidazole class of compounds, that possess positive inotropic and vasodilatory activities. These pharmacologic effects are caused by selective inhibition of a cAMP-specific phosphodiesterase in the heart and in the smooth muscle of blood vessels. Results obtained
Ver todos los artículos relacionados

Número de artículo de comercio global

SKUGTIN
E1279-10MG04061833629697
E1279-50MG04061833629703

Questions

Reviews

No rating value

Active Filters