Saltar al contenido
Merck

Saltar a

C0605

Z-Asp(O-Me)-Glu(O-Me)-Val-Asp(O-Me) fluoromethyl ketone

≥90% (HPLC)

Sinónimos:

Z-DEVD-FMK

Iniciar sesión para ver los precios por organización y contrato.

Acerca de este artículo

Fórmula empírica (notación de Hill):
C30H41N4O12F
Número CAS:
Peso molecular:
668.66
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
≥90% (HPLC)
Form:
powder


assay

≥90% (HPLC)

form

powder

color

off-white

solubility

DMSO: ≥20 mg/mL, clear

shipped in

dry ice

storage temp.

−20°C

SMILES string

COC(=O)CC[C@H](NC(=O)[C@H](CC(=O)OC)NC(=O)OCc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF

InChI

1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1

InChI key

GBJVAVGBSGRRKN-JYEBCORGSA-N

Biochem/physiol Actions

A cell-permeable inhibitor of caspase 3, 6, 7, 8, 10, which exhibits competitive and irreversible inhibition.

Features and Benefits

This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.


Clase de almacenamiento

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



Elija entre una de las versiones más recientes:

Certificados de análisis (COA)

Lot/Batch Number

¿No ve la versión correcta?

Si necesita una versión concreta, puede buscar un certificado específico por el número de lote.

¿Ya tiene este producto?

Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.

Visite la Librería de documentos



Eileen Looby et al.
BMC cancer, 9, 190-190 (2009-06-19)
The progression from Barrett's metaplasia to adenocarcinoma is associated with the acquirement of an apoptosis-resistant phenotype. The bile acid deoxycholate (DCA) has been proposed to play an important role in the development of esophageal adenocarcinoma, but the precise molecular mechanisms
Ji-An Zhao et al.
Oncology letters, 12(5), 4252-4262 (2016-11-30)
Curcumin (CUR) has been demonstrated to protect against carcinogenesis and to prevent tumor development in cancer; however, the clinical application of CUR is limited by its instability and poor metabolic properties. The present study offers an strategy for a novel
Xiao Feng et al.
Cancer letters, 385, 12-20 (2016-11-09)
Vascular recovery or re-angiogenesis after radiotherapy plays a significant role in tumor recurrence, whereas molecular mechanisms of this process remain elusive. In this work, we found that dying glioma cells promoted post-irradiation angiogenesis through a caspase 3 dependent mechanism. Evidence



Número de artículo de comercio global

SKUGTIN
C0605-3MG04061833269367

Questions

Reviews

No rating value

Active Filters