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A5879

2-(2-Aminoethyl)isothiourea dihydrobromide

Name: 2-(2-Aminoethyl)isothiourea dihydrobromide
Brand: SIGMA
Price: 2135 MXP

≥98% (TLC), NOS inhibitor, powder

Sinónimos:

2-(2-Aminoethyl)-2-thiopseudourea dihydrobromide, AET, S-(2-Aminoethyl)isothiouronium bromide hydrobromide

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Tamaño de envase	SKU	Disponibilidad	Precio
25 g		Comprobar disponibilidad del carrito	MXP 2,135.00
100 g		Comprobar disponibilidad del carrito	MXP 6,693.00

Acerca de este artículo

Fórmula lineal:

NH₂CH₂CH₂SC(=NH)NH₂ · 2HBr

Número CAS:

56-10-0

Peso molecular:

281.01

NACRES:

NA.77

PubChem Substance ID:

24278229

UNSPSC Code:

12352200

EC Number:

200-257-0

MDL number:

MFCD00037011

Beilstein/REAXYS Number:

3911163

Assay:

≥98% (TLC)

Form:

powder

Quality level:

100

MXP 2,135.00

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Propiedades

Nombre del producto

2-(2-Aminoethyl)isothiourea dihydrobromide,

assay

≥98% (TLC)

Quality Level

100

form

powder

mp

190-196 °C (lit.)

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless to yellow

SMILES string

Br[H].Br[H].NCCSC(N)=N

InChI

1S/C3H9N3S.2BrH/c4-1-2-7-3(5)6;;/h1-2,4H2,(H3,5,6);2*1H

InChI key

XDVMCVGTDUKDHL-UHFFFAOYSA-N

Gene Information

human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

Descripción

Application

2-(2-Aminoethyl)isothiourea dihydrobromide inhibits nitric oxide synthase (NOS).

Biochem/physiol Actions

Inhibits constitutive and inducible NOS.

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Este artículo	I135	SML1112	G019
Sigma-Aldrich A5879 2-(2-Aminoethyl)isothiourea dihydrobromide	Sigma-Aldrich I135 Imetit dihydrobromide	Sigma-Aldrich SML1112 Remodelin hydrobromide	Sigma-Aldrich G019 Muscimol hydrobromide
assay ≥98% (TLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)	assay ≥98% (HPLC)
form powder	form powder	form powder	form solid
Quality Level 100	Quality Level 100	Quality Level 100	Quality Level 100
solubility water: 50 mg/mL, clear to very slightly hazy, colorless to yellow	solubility H₂O: 20 mg/mL, clear	solubility DMSO: 20 mg/mL, clear	solubility H₂O: >10 mg/mL
mp 190-196 °C (lit.)	mp -	mp -	mp -
Gene Information human ... NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)	Gene Information human ... HRH3(11255)	Gene Information -	Gene Information human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562)

pictograms

GHS07

signalword

Warning

hcodes

H302,H315,H319,H335

pcodes

P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análisis (COA)

Lot/Batch Number

0000435571

0000482458

0000429609

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Differential effect of 2-aminoethyl-isothiourea, an inhibitor of the inducible nitric oxide synthase, on microvascular blood flow and organ injury in models of hepatic ischemia-reperfusion and endotoxemia.

Y Wang et al.

Shock (Augusta, Ga.), 10(1), 20-25 (1998-08-04)

The vasodilator nitric oxide (NO) is involved in the regulation of systemic blood pressure and local organ blood flow. Inhibitors of the constitutively expressed nitric oxide synthase in endothelial cells (eNOS), e.g., Nomega-nitro-L-arginine methyl ester hydrochloride (L-NAME), aggravated liver injury

Polyamines induce rapid biosynthesis of nitric oxide (NO) in Arabidopsis thaliana seedlings.

Ni Ni Tun et al.

Plant & cell physiology, 47(3), 346-354 (2006-01-18)

In this study, we examined the regulation by putrescine, spermidine and spermine of nitric oxide (NO) biosynthesis in Arabidopsis thaliana seedlings. Using a fluorimetric method employing the cell-impermeable NO-binding dye diaminorhodamine-4M (DAR-4M), we observed that the polyamines (PAs) spermidine and

Use of selective and nonselective nitric oxide synthase inhibitors in rat endotoxemia: effects on hepatic morphology and function.

Y Gundersen et al.

Shock (Augusta, Ga.), 8(5), 368-372 (1997-11-15)

Endotoxin has profound effects on nitric oxide (NO) production, and considerable controversies exist as to whether these alterations are beneficial or deleterious. Increased mortality has been reported from nonselective inhibition of NO synthase. Results from selective inhibition of the inducible

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Número de artículo de comercio global

SKU	GTIN
A5879-100G	04061833376553
A5879-25G	04061833376560

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