03907

Tioconazole

97%

• Sinónimos: 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Thioconazole
• Fórmula empírica (notación de Hill): C₁₆H₁₃Cl₃N₂OS
• Número CAS: 65899-73-2
• Peso molecular: 387.71
• PubChem Substance ID: 329747834
• UNSPSC Code: 51302325
• NACRES: NA.85
• EC Number: 265-973-8
• MDL number: MFCD00057276

Propiedades

• Quality Level: 100
• assay: ≥96.5% (HPLC), 96.5-103.5% (NT), 97%
• form: powder
• color: white to off-white
• antibiotic activity spectrum: fungi, yeast
• mode of action: cell membrane | interferes
• SMILES string: Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1
• InChI: 1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2
• InChI key: QXHHHPZILQDDPS-UHFFFAOYSA-N

Descripción

General description

Chemical structure: pyrimidine

Application

Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo[1].

Biochem/physiol Actions

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.

Packaging

10G

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Información de seguridad

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H317,H361d,H410
• pcodes: P202 - P273 - P280 - P301 + P312 - P302 + P352 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - Skin Sens. 1
• Clase de almacenamiento: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves