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UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
polyclonal
Species reactivity:
human
Application:
ELISA, IHC
Citations:
1
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Servicio técnico
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Permítanos ayudarlebiological source
rabbit
Quality Segment
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... LDLR(3949)
Immunogen
Epitope: HOCL oxidized
Hypochlorite-modified LDL.
Application
Immunohistochemistry: 1:50-1:400
ELISA: 1:400-1:4,000
Optimal working dilutions must be determined by the end user.
ELISA: 1:400-1:4,000
Optimal working dilutions must be determined by the end user.
Research Category
Metabolism
Metabolism
Research Sub Category
Lipid Metabolism & Weight Regulation
Lipid Metabolism & Weight Regulation
This Anti-Low Density Lipoprotein Antibody, HOCL oxidized is validated for use in ELISA, IH for the detection of Low Density Lipoprotein.
Biochem/physiol Actions
Reacts strongly and very specifically with HOCL-LDL. By time resolved fluorescence there was no detectable cross reactivity to unmodified LDL has been observed. However weak cross reactivity with MDA-LDL (20%), HNE-LDL (5%) and minimally modified LDL (5%) was observed. By Western blot no detectable cross reactivity to unmodified LDL was observed. Weak cross reactivity (<10%) was detected with MDA-LDL, HNE-LDL and 24 hour Cu2+ oxidized LDL. By ELISA the antibody bound to early and late stages of HOCL-LDL but only weakly (<5%) to several other modifications including MDA-LDL, Cu2-ox-LDL, MDA-HSA and native LDL.
Physical form
Rabbit serum.
Preparation Note
Maintain lyophilized material at -20°C for up to 6 months After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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