900847

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid

≥95%

• Szinonimák: Carboxyl sulfonyl fluoride TMS-alkyne, Probe building block
• Tapasztalati képlet (Hill-képlet): C₁₂H₁₃FO₄SSi
• CAS-szám: 2088828-92-4
• Molekulatömeg: 300.38
• UNSPSC kód: 12352106
• NACRES: NA.22

Tulajdonságok

• Teszt: ≥95%
• form: powder or crystals
• tárolási hőmérséklet: −20°C
• SMILES string: OC(C1=CC(C#C[Si](C)(C)C)=C(S(F)(=O)=O)C=C1)=O

Leírás

Alkalmazás

4-(Fluorosulfonyl)-3-((trimethylsilyl)ethynyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Egyéb megjegyzések

Technology Spotlight: Trifunctional Probe Building Blocks
Chemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable