850365P

18:0 PC (DSPC)

Avanti Research^™ - A Croda Brand

• Szinonimák: 1,2-dioctadecanoyl-sn-glycero-3-phosphocholine; DSPC; PC(18:0/18:0)
• Tapasztalati képlet (Hill-képlet): C₄₄H₈₈NO₈P
• CAS-szám: 816-94-4
• Molekulatömeg: 790.15
• MDL-szám: MFCD00036905
• UNSPSC kód: 51191904
• NACRES: NA.25

Tulajdonságok

• leírás: 1,2-distearoyl-sn-glycero-3-phosphocholine
• Teszt: >99% (TLC)
• Forma: powder
• kiszerelés: pkg of 1 × 1 g (850365P-1G); pkg of 1 × 200 mg (850365P-200MG); pkg of 1 × 25 mg (850365P-25MG); pkg of 1 × 500 mg (850365P-500MG)
• gyártó/kereskedő neve: Avanti Research^™ - A Croda Brand
• alkalmazás(ok): advanced drug delivery
• lipidtípus: phospholipids; cardiolipins
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• SMILES string: [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O
• InChI: 1S/C44H88NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h42H,6-41H2,1-5H3/t42-/m1/s1
• Nemzetközi kémiai azonosító kulcs: NRJAVPSFFCBXDT-HUESYALOSA-N

Leírás

Általános leírás

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is a phospholtidylcholine with alkyl chain comprising 18 carbons. It has phophatidylcholine head group and its structure is similar to 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC).

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Alkalmazás

18:0 PC (DSPC) has been used:

• in the microbubble monolayer preparation for biomolecule delivery studies into protoplasts
• in the preparation of liposomes for immobilization studies
• in the generation of porphyrin-phospholipid (PoP) liposomes for irinotecan (IRT) and doxorubicin delivery

Biokémiai/fiziológiai hatások

1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC) is used in combination with other members of phosphatidylcholine for the generation of mixed bilayer system. It is majorly used in conventional and stealth liposome preparation for drug delivery studies.

Kiszerelés

20 mL Clear Glass Screw Cap Vial (850365P-1G)

20 mL Clear Glass Screw Cap Vial (850365P-500MG)

5 mL Amber Glass Screw Cap Vial (850365P-200MG)

5 mL Amber Glass Screw Cap Vial (850365P-25MG)

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable