E1001

Ethisterone

synthetic (organic), ≥99% (HPLC), Danazol metabolite, powder

• Synonyme(s) : 17α-éthynyltestostérone, 17β-hydroxy-4,17α-pregnène-20-yn-3-one, 4,17α-pregnène-17β-ol-20-yn-3-one
• Formule empirique (notation de Hill) : C₂₁H₂₈O₂
• Numéro CAS: 434-03-7
• Poids moléculaire : 312.45
• NACRES: NA.77
• PubChem Substance ID: 24894377
• UNSPSC Code: 12352200
• EC Number: 207-096-5
• MDL number: MFCD00003656
• Beilstein/REAXYS Number: 1889895
• Assay: ≥99% (HPLC)
• Form: powder

Propriétés

• Nom du produit: Ethisterone, ≥99% (HPLC)
• biological source: synthetic (organic)
• Quality Segment: 200
• sterility: non-sterile
• assay: ≥99% (HPLC)
• form: powder
• drug control: regulated under CDSA - not available from Sigma-Aldrich Canada
• technique(s): cell culture | mammalian: suitable
• mp: 263-269 °C (lit.)
• solubility: chloroform: methanol (1:1): 20 mg/mL, clear to slightly hazy, colorless to light yellow
• originator: Novartis
• shipped in: ambient
• storage temp.: room temp
• SMILES string: C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@@]4(C)[C@H]3CC[C@@]4(O)C#C
• InChI: 1S/C21H28O2/c1-4-21(23)12-9-18-16-6-5-14-13-15(22)7-10-19(14,2)17(16)8-11-20(18,21)3/h1,13,16-18,23H,5-12H2,2-3H3/t16-,17+,18+,19+,20+,21+/m1/s1
• InChI key: CHNXZKVNWQUJIB-CEGNMAFCSA-N

Description

General description

Ethisterone is a progestogen. It is a danazol derivative.

Application

Ethisterone has been used as a component in Dulbecco′s modified eagle medium (DMEM) to culture the transfected COS-7 cell for transient transfection assay and gene transfection assay.

Biochem/physiol Actions

Ethisterone acts as a progestational agent. It is consumed by pregnant mothers to prevent miscarriage.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informations sur la sécurité

• pictograms: GHS08,GHS09
• signalword: Danger
• hcodes: H360FD,H410
• pcodes: P201 - P202 - P273 - P280 - P308 + P313 - P391
• Hazard Classifications: Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 1A
• Classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges