D6035

Disopyramide phosphate salt

• Synonyme(s) : α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide
• Formule linéaire : C₂₁H₂₉N₃O · H₃PO₄
• Numéro CAS: 22059-60-5
• Poids moléculaire : 437.47
• NACRES: NA.77
• PubChem Substance ID: 24277706
• UNSPSC Code: 12352200
• EC Number: 244-756-1
• MDL number: MFCD00069254
• Form: solid

Propriétés

• form: solid
• Quality Segment: 200
• SMILES string: OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C
• InChI: 1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)
• InChI key: CGDDQFMPGMYYQP-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

Description

Application

Disopyramide phosphate salt has been used as an internal standard for plasma sample analysis by mass spectrometry.[1] It might be used as a test compound in a teratogenicity study.[2]

Biochem/physiol Actions

Disopyramide is found to stabilize the cell membrane by altering the action potential. It might act as an antiarrhythmic agent.

Class IA antiarrhythmic; sodium channel blocker

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• ppe: dust mask type N95 (US), Eyeshields, Gloves