This product is intended for research use only. In vitro and in vivo studies have been conducted for research purposes. This product has been cited in a number of publications. Please see the link below to review the current peer reviewed papers:
https://www.sigmaaldrich.com/US/en/search/d047?focus=papers&page=1&perpage=30&sort=relevance&term=D047&type=citation_search
D047
(±)-SKF-38393 hydrochloride
≥98% (HPLC), D1 dopamine receptor agonist, crystalline
Synonyme(s) :
(±)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol hydrochloride
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| Conditionnement | Référence | Disponibilité | Prix |
|---|---|---|---|
| 100 mg | Vérifier la disponibilité des articles du panier | 254,00 € | |
| 500 mg | Vérifier la disponibilité des articles du panier | 845,00 € | |
| 1 g | Vérifier la disponibilité des articles du panier | 1 160,00 € |
A propos de cet article
Formule empirique (notation de Hill) :
C16H17NO2 · HCl
Numéro CAS:
Poids moléculaire :
291.77
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
crystalline
Quality level:
Storage condition:
desiccated, protect from light
Service technique
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Laissez-nous vous aiderNom du produit
(±)-SKF-38393 hydrochloride, crystalline, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
crystalline
storage condition
desiccated, protect from light
color
white
solubility
H2O: >5 mg/mL, aqueous base: soluble (unstable)
SMILES string
Cl.Oc1cc2CCNCC(c3ccccc3)c2cc1O
InChI
1S/C16H17NO2.ClH/c18-15-8-12-6-7-17-10-14(13(12)9-16(15)19)11-4-2-1-3-5-11;/h1-5,8-9,14,17-19H,6-7,10H2;1H
InChI key
YEWHJCLOUYPAOH-UHFFFAOYSA-N
Gene Information
human ... DRD1(1812)
Application
(±)-SKF-38393 hydrochloride has been used as a selective D1 receptor agonist as a part of dopaminergic treatment. It has also been used to study its effect on prolactin in male baboons.
Biochem/physiol Actions
(±)-SKF-38393 is a D1 dopamine receptor agonist. It is known to promote the production of glutamate in the hippocampus.
Disclaimer
This material is hygroscopic. Air-sensitive. Light-sensitive.
1 of 1
Cet article | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| form crystalline | form solid | form solid | form solid |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| solubility H2O: >5 mg/mL, aqueous base: soluble (unstable) | solubility H2O: >5 mg/mL | solubility DMSO: >20 mg/mL, H2O: insoluble | solubility H2O: 1.7 mg/mL, DMSO: >10 mg/mL, ethanol: 6.3 mg/mL |
| storage condition desiccated, protect from light | storage condition desiccated, protect from light | storage condition - | storage condition desiccated |
| Gene Information human ... DRD1(1812) | Gene Information human ... DRD1(1812) | Gene Information human ... DRD1(1812) | Gene Information human ... DRD1(1812) |
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Classe de stockage
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.
Stimulation of dopamine D1 receptor improves learning capacity in cooperating cleaner fish
Messias JPM, et al.
Proc. Royal Soc. Lond. B., 283(1823), 20152272-20152272 (2016)
The D1 dopamine receptor agonist SKF-38393 stimulates the release of glutamate in the hippocampus
Bouron A and Reuter H
Neuroscience, 94(4), 1063-1070 (1999)
Dopamine disruption increases cleanerfish cooperative investment in novel client partners
Soares MC, et al.
Royal Society open science, 4(5), 160609-160609 (2017)
Numéro d'article de commerce international
| Référence | GTIN |
|---|---|
| D047-100MG | 04061833557693 |
| D047-500MG | 04061832090054 |
| D047-1G | 04061825982144 |
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is this crossed the preclinical studies as in invitro and invivo for parkinson's disease
1 réponse-
Utile ?
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