01423

N-Acetyl-D-penicillamine

≥99.0% (T)

• Synonyme(s) : NAP, NAPA, N-Acetyl-3-mercapto-D-valine
• Formule empirique (notation de Hill) : C₇H₁₃NO₃S
• Numéro CAS: 15537-71-0
• Poids moléculaire : 191.25
• NACRES: NA.26
• PubChem Substance ID: 329747269
• UNSPSC Code: 12352116
• EC Number: 239-585-4
• MDL number: MFCD00078887
• Beilstein/REAXYS Number: 1724742

Propriétés

• grade: derivatization grade ((HPLC))
• Quality Segment: 100
• assay: ≥99.0% (T)
• form: powder or crystals
• optical activity: [α]20/D +10±2°, c = 1% in ethanol
• technique(s): HPLC: suitable (derivatization)
• color: white
• mp: 185-190 °C (dec.)
• application(s): peptide synthesis
• SMILES string: CC(=O)N[C@@H](C(O)=O)C(C)(C)S
• InChI: 1S/C7H13NO3S/c1-4(9)8-5(6(10)11)7(2,3)12/h5,12H,1-3H3,(H,8,9)(H,10,11)/t5-/m0/s1
• InChI key: MNNBCKASUFBXCO-YFKPBYRVSA-N

Description

Application

Chiral reagent for the precolumn derivatization of amino acids or amino alcohols; the diastereoisomers formed can be efficiently resolved by HPLC on conventional reversed-phase columns[1]

Biochem/physiol Actions

N-Acetyl-D-penicillamine (NAP or NAPA), a thiol compound, is often used as a control molecule in studies involving nitric oxide donor molecules such as S-nitroso-N-acetyl-dl-penicillamine (SNAP) and sodium nitroprusside (SNP). N-acetyl-D-penicillamine (NAPA) is also used as a heavy metal chelator.

Other Notes

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Informations sur la sécurité

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe de stockage: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves