P1431
Calmodulin from bovine testes
BioUltra, ≥98% (SDS-PAGE), lyophilized powder, essentially salt free
Szinonimák:
CaM, Phosphodiesterase 3′:5′-cyclic nucleotide activator
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(4)
About This Item
Javasolt termékek
biológiai forrás
bovine testis
Minőségi szint
termékcsalád
BioUltra
Teszt
≥98% (SDS-PAGE)
form
lyophilized powder
molekulatömeg
16.79 kDa
tárolási körülmény
(Keep container tightly closed in a dry and well-ventilated place)
technika/technikák
ligand binding assay: suitable
szennyeződések
salt, essentially free
UniProt elérési szám
alkalmazás(ok)
cell analysis
tárolási hőmérséklet
−20°C
Géninformáció
cow ... CALM3(520277)
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Általános leírás
Research area: Cell Signaling
Calmodulin (CaM) is a Ca2+-sensor protein containing four EF-hand motifs that bind to four Ca2+ ions. It is found ubiquitously in all eukaryotes.
Calmodulin (CaM) is a Ca2+-sensor protein containing four EF-hand motifs that bind to four Ca2+ ions. It is found ubiquitously in all eukaryotes.
Alkalmazás
Calmodulin from bovine testes has been used:
- as a component of the reaction mixture in PhosphoSens assay to measure Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα) substrate phosphorylation
- to generate standard curve for the determination of in situ calmodulin concentration in tissues
- as a ligand in radio-ligand binding for studying calmodulin affinity
Biokémiai/fiziológiai hatások
Calmodulin (CaM) aids in the Ca2+ signal transduction pathway in higher plants and animals. Ca2+ binding is required for CaM activation. Upon activation, CaM binds and activates numerous target proteins involved in a variety of cellular processes including regulation of plant metabolism, phytohormone signaling, ion transport, protein folding, protein phosphorylation and dephosphorylation, cell motility, exocytosis, and cytoskeletal assembly. In neurons, calcium-activated CaM helps in the regulation of glutamate receptors, modulation of proteins in signaling pathways, and regulation of voltage-gated calcium channels (VGCCs) activity.
Ca2+ binding protein that is required for activation of cyclic nucleotide-dependent phosphodiesterase. It is also a cofactor/activator of nitric oxide synthase, calcineurin, and many kinases including ATPase, myosin light chain kinase, and CAM kinase I, II, and III. It mediates ryanodine receptor activation by cyclic ADP ribose and is involved in intracellular Ca2+ homeostasis.
antitest
Product No.
Leírás
Árazás
kapcsolódó termék
Product No.
Leírás
Árazás
Tárolási osztály kódja
11 - Combustible Solids
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Egyéni védőeszköz
Eyeshields, Gloves, type N95 (US)
Analitikai tanúsítványok (COA)
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