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I0020000

Ibuprofen

European Pharmacopoeia (EP) Reference Standard

Szinonimák:

α-Methyl-4-(isobutyl)phenylacetic acid, (±)-2-(4-Isobutylphenyl)propanoic acid

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)

About This Item

Tapasztalati képlet (Hill-képlet):
C13H18O2
CAS-szám:
15687-27-1
Molekulatömeg:
206.28
MDL-szám:
MFCD00010393
UNSPSC kód:
41116107
PubChem Substance ID:
329815293
NACRES:
NA.24

grade

pharmaceutical primary standard

API-család

ibuprofen

gyártó/kereskedő neve

EDQM

alkalmazás(ok)

pharmaceutical (small molecule)

format

neat

SMILES string

CC(C)Cc1ccc(cc1)C(C)C(O)=O

InChI

1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)

Nemzetközi kémiai azonosító kulcs

HEFNNWSXXWATRW-UHFFFAOYSA-N

Géninformáció

human ... PTGS1(5742) , PTGS2(5743)

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Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Ibuprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biokémiai/fiziológiai hatások

Cyclooxygenase (COX) inhibitor that has greater activity against COX-1 than against COX-2.

Kiszerelés

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Egyéb megjegyzések

Sales restrictions may apply.

kapcsolódó termék

Product No.
Leírás
Árazás

PHR1146

Ibuprofen Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

1335508

Ibuprofen, United States Pharmacopeia (USP) Reference Standard

1335541

Ibuprofen Related Compound C, United States Pharmacopeia (USP) Reference Standard

B1220000

Ibuprofen impurity B, European Pharmacopoeia (EP) Reference Standard

Y0000140

Ibuprofen impurity F, European Pharmacopoeia (EP) Reference Standard

Y0000881

Ibuprofen for peak identification, European Pharmacopoeia (EP) Reference Standard

61849

2-[4-(2-Methylpropyl)phenyl]ethanol, pharmaceutical impurity standard

1335596

Ibuprofen Related Compound J, United States Pharmacopeia (USP) Reference Standard

PHR1934

Ibuprofen Impurity B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1964

Ibuprofen Impurity F, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1933

Ibuprofen Impurity A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1935

Ibuprofen Impurity N, Pharmaceutical Secondary Standard; Certified Reference Material

BP539

Ibuprofen, British Pharmacopoeia (BP) Reference Standard

BP557

4′-Isobutylacetophenone, British Pharmacopoeia (BP) Reference Standard

PHR2028

Ibuprofen Impurity H, Pharmaceutical Secondary Standard; Certified Reference Material

PHR1965

Ibuprofen Impurity G, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2122

2-(4-Isobutyrylphenyl)propanamide, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2146

2-(4-Isobutylphenyl)-N-(1-phenylethyl)propionamide, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2141

2-(4-Isobutylphenyl)prop-2-enoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2136

4-(1-Hydroxy-2-methylpropyl)-acetophenone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2143

Ibuprofen 2,3-Butylene Glycol Ester, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2142

Ibuprofen 1,3-Butylene Glycol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

BP880

Ibuprofen impurity B, British Pharmacopoeia (BP) Reference Standard

PHR2124

4-Isobutyrylacetophenone, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2145

Ibuprofen 1,2-Propanetriol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2144

Ibuprofen 1,2-Propylene Glycol Esters, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2483

4-Acetylbenzoic Acid, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2138

Ibuprofen Ethyl Ester

PHR2125

2-(4-Isobutyrylphenyl)propane

PHR2127

2-(4-n-Propylphenyl)propanoic Acid

PHR2129

Isopropyl 2-(4-Isobutylphenyl)propanoate

PHR2130

1-Ethyl-4-isobutylbenzene

PHR2134

4-Isobutylstyrene

PHR2135

1-(4-Isobutylphenyl)ethanol

PHR2132

2-[4-(2-Hydroxy-2-methylpropyl)-phenyl]propanoic Acid, certified reference material, pharmaceutical secondary standard

PHR2137

Ibuprofen Methyl Ester, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2133

Ibuprofen Intermediate, certified reference material, pharmaceutical secondary standard

PHR2126

2-Hydroxypropyl 2-(4-Isobutylphenyl)-propanoate, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2269

4-Isobutylbenzoic acid, Pharmaceutical Secondary Standard; Certified Reference Material

Piktogramok

Exclamation mark
GHS07

Figyelmeztetés

Warning

Figyelmeztető mondatok

H302,H319,H335

Veszélyességi osztályok

Acute Tox. 4 Oral - Eye Irrit. 2 - STOT SE 3

Célzott szervek

Respiratory system

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number

Sajnos jelenleg COA nem áll rendelkezésre ehhez a termékhez online.

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Dokumentumtár megtekintése

J B Whitlam et al.
Clinical pharmacology and therapeutics, 29(4), 487-492 (1981-04-01)
Free and total ibuprofen levels in serum and synovial fluid (SF) were determined in one male and 14 female arthritic patients (mean age 56 yr, range 19 to 77) after 400 mg three times daily for 2 days. Free drug
R O Day et al.
Clinical pharmacology and therapeutics, 43(5), 480-487 (1988-05-01)
The simultaneous disposition of the enantiomers of ibuprofen in synovial fluid and plasma was studied in eight patients with arthritis. Concentrations of the active S-enantiomer in synovial fluid exceeded those of the R-enantiomer at all times in all patients with
Sheena Derry et al.
The Cochrane database of systematic reviews, 10(10), CD007550-CD007550 (2013-10-24)
This review is an update of a previously published review in The Cochrane Database of Systematic Reviews Issue 3, 2009 on single dose oral dexibuprofen (S(+)-ibuprofen) for acute postoperative pain in adults.Dexibuprofen is a non-steroidal anti-inflammatory drug (NSAID) licensed for
Roland Neumann et al.
Neonatology, 102(1), 9-15 (2012-03-15)
Pharmacological closure of patent ductus arteriosus (PDA) is commonly achieved by intravenous (IV) administration of ibuprofen or indomethacin. Occasionally, oral ibuprofen is used for PDA treatment although its efficacy and safety are unclear. To systematically review randomized and quasi-randomized trials
Massimo Imazio et al.
The New England journal of medicine, 369(16), 1522-1528 (2013-09-03)
Colchicine is effective for the treatment of recurrent pericarditis. However, conclusive data are lacking regarding the use of colchicine during a first attack of acute pericarditis and in the prevention of recurrent symptoms. In a multicenter, double-blind trial, eligible adults
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