857123P

16:0 Lyso PA

Avanti Research^™ - A Croda Brand

• Szinonimák: 1-hexadecanoyl-sn-glycero-3-phosphate (sodium salt); palmitoyl lysophosphatidic acid; PA(16:0/0:0); 16:0 LPA; 110678
• Tapasztalati képlet (Hill-képlet): C₁₉H₃₈O₇PNa
• CAS-szám: 17618-08-5
• Molekulatömeg: 432.46
• MDL-szám: MFCD00133396
• UNSPSC kód: 51191904
• NACRES: NA.25

Tulajdonságok

• leírás: 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
• Teszt: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Forma: powder
• kiszerelés: pkg of 1 × 200 mg (857123P-200mg); pkg of 1 × 25 mg (857123P-25mg)
• gyártó/kereskedő neve: Avanti Research^™ - A Croda Brand
• lipidtípus: phospholipids; cardiolipins
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C

Leírás

Általános leírás

Lysophosphatidic acid (LPA) belongs to a class of phospholipids, that has a glycerol backbone attached by a phosphate group, an aliphatic chain and a hydroxyl group. It has a phosphate group attached to sn-3 position, an aliphatic chain attached to sn-1 or sn-2 position and the hydroxyl group attached to the remaining sn-1 or sn-2 position.

Alkalmazás

16:0 Lyso PA is suitable to use as an internal standard to extract lipids from plasma sample of ovarian cancer patients. It is also suitable for the preparation of lipid solutions for synthesizing liposomes.

Biokémiai/fiziológiai hatások

Lysophosphatidic acid (LPA) participates in several biological functions. It acts as a potential biomarker for detecting ovarian cancer. LPA stimulates platelet aggregation, smooth muscle contraction, chemotaxis, cytoskeleton rearrangement, Ca²⁺ mobilization, neurotransmitter release and cell proliferation. Palmitoyl-lysophosphatidic acid helps in increasing aggregation, stimulated by adenosine diphosphate (ADP).

Kiszerelés

5 mL Amber Glass Screw Cap Vial (857123P-200mg)

5 mL Amber Glass Screw Cap Vial (857123P-25mg)

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids