857128P

18:0 Lyso PA

Avanti Research^™ - A Croda Brand

• Szinonimák: 1-octadecanoyl-sn-glycero-3-phosphate (sodium salt); stearoyl lysophosphatidic acid; PA(18:0/0:0); 18:0 LPA; s-LPA; 110680
• Tapasztalati képlet (Hill-képlet): C₂₁H₄₂O₇PNa
• CAS-szám: 325465-92-7
• Molekulatömeg: 460.52
• UNSPSC kód: 51191904
• NACRES: NA.25

Tulajdonságok

• leírás: 1-stearoyl-2-hydroxy-sn-glycero-3-phosphate (sodium salt)
• Teszt: >99% (LPA; may contain up to 10% of the 2-LPA isomer, TLC)
• Forma: powder
• kiszerelés: pkg of 1 × 25 mg (857128P-25mg)
• gyártó/kereskedő neve: Avanti Research^™ - A Croda Brand
• lipidtípus: cardiolipins; phospholipids
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• SMILES string: O[C@](COP([O-])(O)=O)([H])COC(CCCCCCCCCCCCCCCCC)=O.[Na+]

Leírás

Általános leírás

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA), a bioactive phospholipid is seen at a low level in plasma (~100nM). It is usually formed during the synthesis of phospholipid of cell membranes. It is produced by various cells like, activated platelets, epithelial cells, leukocytes, neuronal cells and tumor cells. 18:0 Lyso PA has stearic acid at sn-1 and a hydroxyl group at sn-2 position.

Alkalmazás

18:0 Lyso PA is suitable for use:

• to determine the extraction recovery of LPA at neutral pH and acidic pH by chromatographic method
• to use as internal standard to study the role of intestinally derived lysophosphatidic acid in dyslipidemia and atherosclerosis
• to investigate its effects on clathrin?dependent endocytosis

Biokémiai/fiziológiai hatások

Lysophosphatidic acid (1- or 2-acyl-lysophosphatidic acid/LPA) modulates cell motility, proliferation, invasion, survival and production of growth factors via G protein-coupled receptor (GPCR).

Kiszerelés

5 mL Amber Glass Screw Cap Vial (857128P-25mg)

Jogi információk

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 3