PHR1051
Propylene glycol
Pharmaceutical Secondary Standard; Certified Reference Material
Szinonimák:
1,2-Propanediol, Propylene glycol
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
Lineáris képlet:
CH3CH(OH)CH2OH
CAS-szám:
Molekulatömeg:
76.09
Beilstein:
1340498
EC-szám:
MDL-szám:
UNSPSC kód:
41116107
PubChem Substance ID:
E szám:
E1520
NACRES:
NA.24
Javasolt termékek
grade
certified reference material
pharmaceutical secondary standard
Minőségi szint
Ügynökség
traceable to USP 1576708
gőzsűrűség
2.62 (vs air)
gőznyomás
0.08 mmHg ( 20 °C)
API-család
propylene glycol
Analitikai műbizonylat
current certificate can be downloaded
öngyulladási hőmérséklet
779 °F
robbanási határérték
12.5 %
technika/technikák
HPLC: suitable
gas chromatography (GC): suitable
törésmutató
n20/D 1.432 (lit.)
bp
187 °C (lit.)
mp
−60 °C (lit.)
sűrűség
1.036 g/mL at 25 °C (lit.)
alkalmazás(ok)
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
pharmaceutical (small molecule)
format
neat
tárolási hőmérséklet
2-30°C
SMILES string
CC(O)CO
InChI
1S/C3H8O2/c1-3(5)2-4/h3-5H,2H2,1H3
Nemzetközi kémiai azonosító kulcs
DNIAPMSPPWPWGF-UHFFFAOYSA-N
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Általános leírás
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propylene glycol is commonly utilized as a penetration enhancer in topical dermatological formulations, either alone or in combined form with other penetration enhancing agents, like fatty acids.
Propylene glycol is commonly utilized as a penetration enhancer in topical dermatological formulations, either alone or in combined form with other penetration enhancing agents, like fatty acids.
Alkalmazás
Propylene glycol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Analízis megjegyzés
These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Egyéb megjegyzések
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Lábjegyzet
To see an example of a Certificate of Analysis for this material enter LRAB9658 in the slot below. This is an example certificate only and may not be the lot that you receive.
Javasolt termékek
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
Alkalmazás
Product No.
Leírás
Árazás
kapcsolódó termék
Product No.
Leírás
Árazás
Tárolási osztály kódja
10 - Combustible liquids
WGK
WGK 1
Lobbanási pont (F)
219.2 °F - closed cup
Lobbanási pont (C)
104 °C - closed cup
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Analysis of aldehydes in excipients used in liquid/semi-solid formulations by gas chromatography-negative chemical ionization mass spectrometry
Li Z, et al.
Journal of Chromatography A, 1160(1-2), 299-305 (2007)
Effect of finite doses of propylene glycol on enhancement of in vitro percutaneous permeation of loperamide hydrochloride
Trottet L, et al.
International Journal of Pharmaceutics, 274(1-2), 213-219 (2004)
Rong-Yao Wang et al.
Physical chemistry chemical physics : PCCP, 15(9), 3313-3319 (2013-01-31)
Understanding the role of kinetics in fiber network microstructure formation is of considerable importance in engineering gel materials to achieve their optimized performances/functionalities. In this work, we present a new approach for kinetic-structure analysis for fibrous gel materials. In this
J O Funk et al.
Contact dermatitis, 31(4), 236-241 (1994-10-01)
Evaluation of dermatitis associated with propylene glycol application or ingestion remains a challenge. The research dealing with skin reactions to propylene glycol is revisited and new aspects for future research are outlined. Based on literature review and our own observations
G A Reichard et al.
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