PHR1045

Diethylene glycol

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: DEG, 2,2′-Oxydiethanol, 2-Hydroxyethyl ether, Bis(2-hydroxyethyl) ether, Diglycol
• Lineáris képlet: (HOCH₂CH₂)₂O
• CAS-szám: 111-46-6
• Molekulatömeg: 106.12
• Beilstein: 969209
• EC-szám: 203-872-2
• MDL-szám: MFCD00002882
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823075
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to Ph. Eur. Y0000217; traceable to USP 1193265
• gőzsűrűség: 2.14 (vs air)
• gőznyomás: 0.01 mmHg ( 20 °C)
• API-család: diethylene glycol
• Analitikai műbizonylat: current certificate can be downloaded
• öngyulladási hőmérséklet: 442 °F
• robbanási határérték: 2-12.3 %
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• törésmutató: n20/D 1.447 (lit.)
• bp: 245 °C (lit.)
• mp: −10 °C (lit.)
• sűrűség: 1.118 g/mL at 25 °C (lit.)
• alkalmazás(ok): cleaning products; cosmetics; food and beverages; personal care; pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-30°C
• SMILES string: OCCOCCO
• InChI: 1S/C4H10O3/c5-1-3-7-4-2-6/h5-6H,1-4H2
• Nemzetközi kémiai azonosító kulcs: MTHSVFCYNBDYFN-UHFFFAOYSA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Diethylene glycol is a a four carbon dimer of ethylene glycol and finds applications as antifreeze, solvent, humectant, hydraulic fluid and brake fluid. It is a potential neuro- and nephrotoxin for humans. It may also be utilized in moisturizers, lubricants, emulsification agents, additives and solvents.

Alkalmazás

Diethylene glycol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).

Diethylene glycol may be used as a standard in the determination of diethylene glycol present in serum samples using gas chromatography (GC). It may also be used as a reference standard in validating the composition of diethylene glycol in propolis syrup consumed by intoxicated victims using nuclear magnetic resonance studies (NMR) and gas chromatography coupled with flame ionization detector (GC-FID).

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC0277 in the slot below. This is an example certificate only and may not be the lot that you receive.

Javasolt termékek

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H302
• Óvintézkedésre vonatkozó mondatok: P264 - P270 - P301 + P312 - P501
• Veszélyességi osztályok: Acute Tox. 4 Oral
• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): 280.4 °F - closed cup
• Lobbanási pont (C): 138 °C - closed cup