BP576

Hydrocortisone

British Pharmacopoeia (BP) Assay Standard

• Szinonimák: 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M
• Tapasztalati képlet (Hill-képlet): C₂₁H₃₀O₅
• CAS-szám: 50-23-7
• Molekulatömeg: 362.46
• Beilstein: 1354819
• MDL-szám: MFCD00011654
• UNSPSC kód: 41116107
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: hydrocortisone
• form: solid
• eltarthatósági idő: limited shelf life, expiry date on the label
• gyártó/kereskedő neve: BP
• mp: 211-214 °C (lit.)
• alkalmazás(ok): pharmaceutical; pharmaceutical small molecule
• format: neat
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
• InChI: 1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
• Nemzetközi kémiai azonosító kulcs: JYGXADMDTFJGBT-VWUMJDOOSA-N
• Géninformáció: human ... NR3C1(2908)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Hydrocortisone BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Tretinoin, Hydrocortisone and Hydroquinone Cream

Miconazole and Hydrocortisone Acetate Cream

Hydrocortisone Sodium Succinate Injection

Prednisolone Tablets

Miconazole and Hydrocortisone Cream

Miconazole and Hydrocortisone Ointment

Hydrocortisone and Neomycin Cream

Hydrocortisone and Clioquinol Ointment

Hydrocortisone Sodium Phosphate Oral Solution

Prednisolone Gastro-resistant Tablets

Hydrocortisone Sodium Phosphate

Hydrocortisone Sodium Phosphate Injection

Hydrocortisone and Clioquinol Cream

Methylprednisolone Tablets

Hydrocortisone Acetate Oral Suspension

Hydrocortisone Cream

Hydrocortisone Oromucosal Tablets

Biokémiai/fiziológiai hatások

Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na²⁺ retention potency.

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Piktogramok: GHS08
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H360Df,H373
• Óvintézkedésre vonatkozó mondatok: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Veszélyességi osztályok: Repr. 1A - STOT RE 2
• Célzott szervek: Adrenal gland,Bone marrow
• Tárolási osztály kódja: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable