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Merck

GABRA5

gamma-aminobutyric acid (GABA) A receptor, alpha 5

Synonimy:
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2558) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. [provided by RefSeq, Jul 2008]
  • Mouse(110886) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5
  • Rat(29707) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Domestic Rabbit(100340943) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • naked mole-rat(101712275) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic guinea pig(100729411) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Horse(100050880) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • domestic cat(101090773) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • sheep(101115159) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • dog(488688) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • cow(523515) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • chicken(418684) gamma-aminobutyric acid (GABA) A receptor, alpha 5
  • Zebrafish(799124) gamma-aminobutyric acid (GABA) A receptor, alpha 5

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Gaboxadol hydrochloride, solid, ≥98% (HPLC),
Gatunek
human
Isoguvacine hydrochloride, solid,
Gatunek
human
Muscimol hydrobromide, ≥98% (HPLC), solid,
Gatunek
human
Piperidine-4-sulfonic acid, ,
Gatunek
human
Oxazepam, ,
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
Dehydroisoandrosterone 3-sulfate sodium salt dihydrate, ≥93% (TLC), powder,
Gatunek
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Gatunek
human
trans-Dehydroandrosterone, ≥99%,
Gatunek
human, rat
Diazepam for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Propofol, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Ro 15-4513, solid,
Gatunek
rat, human
Picrotoxin, powder,
Gatunek
human
Pregnenolone sulfate sodium salt, ,
Gatunek
human
SR-95531, ≥98% (HPLC), powder,
Gatunek
human
3α,21-Dihydroxy-5α-pregnan-20-one, ≥95%,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GABRA5 (ab2) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
guinea pig, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
Anti GABRA5 Antibody, clone 23GB5505, Rabbit Monoclonal, clone 23GB5505, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
western blot
Monoclonal Anti-GABA A Receptor-Atto 594 antibody produced in mouse, clone S415-24,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor antibody produced in mouse, clone S415-24,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunofluorescence
western blot
Monoclonal Anti-GABA A Receptor-Allophycocyanin antibody produced in mouse, clone S415-24,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunofluorescence
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
NO-711 hydrochloride, ≥98% (HPLC),
Gatunek
human
(±)-Vigabatrin, ,
Gatunek
human
2,6-Diisopropylphenol, 97%,
Gatunek
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
Topiramate, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human

Small Molecule - Ligand

Numer produktu
Opis
Gatunek
L-655,708, ≥98% (HPLC), powder,
Gatunek
human
Etomidate, >98% (HPLC), powder,
Gatunek
human
Flumazenil, >99% (HPLC), solid,
Gatunek
rat, human
Carbamazepine, powder,
Gatunek
rat, human
2-Bromo-2-chloro-1,1,1-trifluoroethane, ≥99%,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GABRA5,
Gatunek
human