U1006

Uridine 5′-triphosphate trisodium salt solution

HPLC purified, aqueous solution for RNA polymerase transcription

• Szinonimák: UTP
• MDL-szám: MFCD00044310
• UNSPSC kód: 41106305
• PubChem Substance ID: 24900622
• NACRES: NA.52

Tulajdonságok

• biológiai forrás: yeast (Candida Utilis)
• Minőségi szint: 300
• Teszt: ≥95 (HPLC)
• Forma: liquid
• koncentráció: 100 mM in H₂O (adjusted to pH 7 with Trizma^®; base)
• szín: colorless
• idegen aktivitás: DNase and RNase, none detected
• kiszállítva: dry ice
• tárolási hőmérséklet: −20°C
• SMILES string: [Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O15P3.3Na/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;;/q;3*+1/p-3/t4-,6-,7-,8-;;;/m1.../s1
• Nemzetközi kémiai azonosító kulcs: MMJGIWFJVDOPJF-LLWADOMFSA-K
• Géninformáció: human ... P2RY2(5029) ; rat ... P2ry2(29597)

Leírás

Alkalmazás

Uridine 5′-triphosphate trisodium salt solution has been used to increase the intracellular Ca²⁺ levels in rat primary tracheal epithelial cells. It has also been used as a nucleotide substrate to analyze the activity of MutT homologue 1 (MTH1).

Biokémiai/fiziológiai hatások

P2Y receptor agonist

UTP plays a crucial role in the process of transcription by participating in the synthesis of RNA. It is associated with glycogen synthesis, protein glycosylation, and membrane phospholipid biosynthesis. UTP is involved in the production of ATP, which is essential for metabolic reactions.

Uridine 5′-triphosphate (UTP) is released during nerve injury and acts as an agonist of the purinergic P2Y2 receptors present on the surface of Schwann cells.

Jogi információk

Trizma is a registered trademark of Merck KGaA, Darmstadt, Germany

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable