Ugrás a tartalomra
Merck

H0878

Sigma-Aldrich

Heparin lithium salt from porcine intestinal mucosa

≥150 USP units/mg

Szinonimák:

Lithium acid heparin, Lithium heparinate

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

CAS-szám:
MDL-szám:
UNSPSC kód:
12352201
NACRES:
NA.25

biológiai forrás

Porcine intestinal mucosa

Minőségi szint

form

powder

specifikus aktivitás

≥150 USP units/mg

szín

off-white

oldhatóság

water: 40 mg/mL, clear, colorless to faint yellow or tan

kation nyomok

Li: 3-4%

alkalmazás(ok)

diagnostic assay manufacturing
life science and biopharma
plasma purification
sample preparation

tárolási hőmérséklet

room temp

InChI

1S/C14H25NO20S3/c1-29-9-7(17)10(35-38(26,27)28)14(34-11(9)12(18)19)33-8-4(3-31-37(23,24)25)32-13(30-2)5(6(8)16)15-36(20,21)22/h4-11,13-17H,3H2,1-2H3,(H,18,19)(H,20,21,22)(H,23,24,25)(H,26,27,28)

Nemzetközi kémiai azonosító kulcs

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Általános leírás

Heparin lithium is a highly sulfated polysaccharide that belongs to the family of glycosaminoglycans with remarkable significance in the areas of cell culture, cancer biology, biochemical, and drug discovery research. Due to its interactions with proteins and cells, it is used to study molecular and cellular processes, tumor modeling, investigate binding interactions, and as a cell culture supplement, to maintain cell viability.

Alkalmazás

Heparin lithium was used:
  • To validate photometric measurements in cell surface charge determination
  • As an anti-coagulant for laboratory studies
  • To study hypothermal stress on lactate metabolism
  • To study the effects of anticoagulants in direct membrane feeding assays
  • For 2D and 3D vitro cell culture in glioblastoma cell models
  • To prevent clot formation and tissue damage during mechanical probing of cardiac pacemaker cell embryonic patterning, a study that contributes to the broader area of cardiac tissue mechanics research and developmental biology

Tulajdonságok és előnyök

  • Heparin with specific activity of ≥150 USP units/mg
  • Versatile and adaptable for a wide variety of laboratory and research applications

Egyéb megjegyzések

For additional information on our range of Biochemicals, please complete this form.
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

R B Shartau et al.
The Journal of experimental biology, 223(Pt 7) (2020-03-05)
Acute (<96 h) exposure to elevated environmental CO2 (hypercarbia) induces a pH disturbance in fishes that is often compensated by concurrent recovery of intracellular and extracellular pH (pHi and pHe, respectively; coupled pH regulation). However, coupled pH regulation may be limited
Beatriz Giesen et al.
Pharmaceutics, 13(2) (2021-03-07)
Gold nanoparticles (Au NPs) are studied as delivery systems to enhance the effect of the glutaminase1 inhibitor CB839, a promising drug candidate already in clinical trials for tumor treatments. Au NPs were synthesized using a bottom-up approach and covered with
Chia-Hao Chang et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 248, 110744-110744 (2020-06-23)
The milkfish Chanos chanos, an economically important cultured marine species in Southeast Asia, exhibits stenothermal and euryhaline characteristics and huge mortality usually occurs during extreme cold weather in winter. Under conditions beyond optimal temperatures, ectothermic species experience an increase in
The effect of anticoagulants in blood collection tubes on Plasmodium falciparum transmission in direct membrane feeding assays
Wouter G et al.
Transactions of the Royal Society of Tropical Medicine and Hygiene, 116, 187- 189 (2022)
Determination of cell surface charge by photometric titration
Thethi K et al
Journal of Biochemical and Biophysical Methods, 34, 137-145 (1997)

Cikkek

Glycosaminoglycans are large linear polysaccharides constructed of repeating disaccharide units.

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