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G7879

Sigma-Aldrich

D-Glucose 6-phosphate sodium salt

≥98% (HPLC)

Szinonimák:

D(+)-Glucopyranose 6-phosphate sodium salt, G-6-P Na, Robison ester

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Összes fotó(5)

About This Item

Tapasztalati képlet (Hill-képlet):
C6H12NaO9P
CAS-szám:
54010-71-8
Molekulatömeg:
282.12
Beilstein:
5787568
EC-szám:
258-921-0
MDL-szám:
MFCD00006611
UNSPSC kód:
12352201
PubChem Substance ID:
24895324
NACRES:
NA.25

biológiai forrás

synthetic (organic)

Minőségi szint

300

Teszt

≥98% (HPLC)

Forma

crystalline

technika/technikák

HPLC: suitable

szín

white

hasznos pH-tartomány

4.0-5.0

mp

204 °C (dec.) (lit.)

oldhatóság

water: 50 mg/mL, clear, colorless to very faintly yellow

kation nyomok

Na: 6.1-10.2% (anhydrous)

tárolási hőmérséklet

room temp

SMILES string

[Na+].O[C@@H]1O[C@H](COP(O)([O-])=O)[C@@H](O)[C@H](O)[C@H]1O

InChI

1S/C6H13O9P.Na/c7-3-2(1-14-16(11,12)13)15-6(10)5(9)4(3)8;/h2-10H,1H2,(H2,11,12,13);/q;+1/p-1/t2-,3-,4+,5-,6-;/m1./s1

Nemzetközi kémiai azonosító kulcs

ZALKNDISPIVVKC-WYRLRVFGSA-M

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Related Categories

Alkalmazás

D-glucose-6-phosphate sodium can be used as an energy source for Mycobacterium tuberculosis.

Biokémiai/fiziológiai hatások

In cells, D-glucose 6-phosphate (G6P) is generated when glucose is phosphorylated by hexokinase or glucokinase or by the conversion of glucose-1-phosphate by phosphoglucomutase during glycogenolysis. G6P lies at the beginning of both glycolysis and the pentose phosphate pathways. It also can be stored as glycogen when blood glucose levels are high.

Vigyázat

Non-hygroscopic, and very stable to atmospheric moisture at room temperature, unlike the disodium salt.

Egyéb megjegyzések

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)

Válasszon a legfrissebb verziók közül:

Analitikai tanúsítványok (COA)

Lot/Batch Number
0000365994
0000365994
0000415171
0000415171
0000405982

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Dokumentumtár megtekintése

Iain J Abbott et al.
The Journal of antimicrobial chemotherapy, 75(4), 988-996 (2019-12-25)
To assess the antibacterial effects of a single 3 g oral fosfomycin dose on Escherichia coli and Klebsiella pneumoniae clinical isolates within a dynamic bladder infection model. An in vitro model simulating dynamic urinary fosfomycin concentrations was used. Target fosfomycin exposure
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(6) (2020-04-08)
There are limited treatment options for enterococcal urinary tract infections, especially vancomycin-resistant Enterococcus (VRE). Oral fosfomycin is a potential option, although limited data are available guiding dosing and susceptibility. We undertook pharmacodynamic profiling of fosfomycin against E. faecalis and E.
Iain J Abbott et al.
Journal of microbiological methods, 171, 105861-105861 (2020-02-09)
The impact of the bladder environment on fosfomycin activity and treatment response is uncertain. Standard laboratory media does not reflect the biomatrix of urine, where limited nutritional factors are important for growth and antimicrobial kill rates. We compared fosfomycin activity
Iain J Abbott et al.
Antimicrobial agents and chemotherapy, 64(3) (2020-01-08)
Oral fosfomycin trometamol is licensed as a single oral dose for the treatment of uncomplicated urinary tract infections, with activity against multidrug-resistant uropathogens. The impact of interindividual variability in urinary concentrations on antimicrobial efficacy, and any benefit of giving multiple
Pascal Belin et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(18), 7426-7431 (2009-05-07)
The gene encoding the cytochrome P450 CYP121 is essential for Mycobacterium tuberculosis. However, the CYP121 catalytic activity remains unknown. Here, we show that the cyclodipeptide cyclo(l-Tyr-l-Tyr) (cYY) binds to CYP121, and is efficiently converted into a single major product in
View All Related Papers

Cikkek

Aerobic Glycolysis and the Warburg Effect

Warburg effect enhances glucose to lactate conversion in tumor cells, regardless of oxygen levels; impacting cancer metabolism since 1924.

Protocols

Enzymatic Activity of Glucose-6-Phosphatase [EC 3.1.3.9]

To measure glucose-6-phosphatase activity, the Taussky-Shorr method is used. This method is a spectrophotometric stop-rate determination assay that is measured at 660 nm.

Enzymatic Assay of Glucose-6-Phosphate Dehydrogenase (EC 1.1.1.49)

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

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