G7403

Glycine

≥99% (titration), suitable for electron microscopy, BioXtra

• Szinonimák: Aminoacetic acid, Aminoethanoic acid, Glycocoll
• Lineáris képlet: NH₂CH₂COOH
• CAS-szám: 56-40-6
• Molekulatömeg: 75.07
• Beilstein: 635782
• EC-szám: 200-272-2
• MDL-szám: MFCD00008131
• UNSPSC kód: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24895306
• NACRES: NA.26

Tulajdonságok

• product name: Glycine, BioXtra, ≥99% (titration)
• termékcsalád: BioXtra
• Minőségi szint: 200
• Teszt: ≥99% (titration)
• form: powder
• technika/technikák: electron microscopy: suitable
• szennyeződések: Insoluble matter, passes filter test
• izzítási maradék: ≤0.05%
• veszteség: ≤0.05% loss on drying, HV, 20-26 °C
• szín: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• mp: 240 °C (dec.) (lit.)
• oldhatóság: 1 M HCl: 1 M, clear, colorless
• anion nyomok: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• kation nyomok: Al: ≤0.0005%; As: ≤0.00001%; Ba: ≤0.0005%; Bi: ≤0.0005%; Ca: ≤0.001%; Cd: ≤0.0005%; Co: ≤0.0005%; Cr: ≤0.0005%; Cu: ≤0.0005%; Fe: ≤0.0005%; K: ≤0.005%; Li: ≤0.0005%; Mg: ≤0.0005%; Mn: ≤0.0005%; Mo: ≤0.0005%; NH₄⁺: ≤0.02%; Na: ≤0.02%; Ni: ≤0.0005%; Pb: ≤0.0005%; Sr: ≤0.0005%; Zn: ≤0.0005%
• absorption: ≤0.04 at 260 in 1 M HCl at 1 M; ≤0.04 at 280 in 1 M HCl at 1 M
• SMILES string: NCC(O)=O
• UV-elnyelés: λ: 260 nm A_max: ≤0.04; λ: 260 nm A_max: 0.003; λ: 260 nm A_max: 0.006
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• Nemzetközi kémiai azonosító kulcs: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Géninformáció: rat ... Grin2a(24409)

Leírás

Alkalmazás

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope. It has also been used for sample fixation in the process of immunolabeling.

Biokémiai/fiziológiai hatások

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)